{"id":5067,"date":"2025-03-01T10:57:00","date_gmt":"2025-03-01T08:57:00","guid":{"rendered":"https:\/\/drmarinov.com\/?p=5067"},"modified":"2025-09-20T19:26:43","modified_gmt":"2025-09-20T16:26:43","slug":"saxenda-otslabvane","status":"publish","type":"post","link":"https:\/\/drmarinov.com\/en\/saxenda-otslabvane\/","title":{"rendered":"Saxenda for weight loss in obesity - price, results and side effects."},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"5067\" class=\"elementor elementor-5067\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-101601fe elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"101601fe\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-194e90d2\" data-id=\"194e90d2\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-30735f7 elementor-button-info elementor-widget elementor-widget-button\" data-id=\"30735f7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-xs\" href=\"#\" id=\"&lt;a href=&quot;https:\/\/drmarinov.com\/en\/tag\/%d0%bd%d0%b0%d1%83%d1%87%d0%bd%d0%be-%d0%b1%d0%b0%d0%b7%d0%b8%d1%80%d0%b0%d0%bd%d0%b0-%d1%81%d1%82%d0%b0%d1%82%d0%b8%d1%8f\/&quot; rel=&quot;tag&quot;&gt;\u043d\u0430\u0443\u0447\u043d\u043e-\u0431\u0430\u0437\u0438\u0440\u0430\u043d\u0430 \u0441\u0442\u0430\u0442\u0438\u044f&lt;\/a&gt;\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">\u041d\u0430\u0443\u0447\u043d\u043e-\u0431\u0430\u0437\u0438\u0440\u0430\u043d\u0430 \u0441\u0442\u0430\u0442\u0438\u044f.<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-23b8341 elementor-toc--minimized-on-tablet elementor-widget elementor-widget-table-of-contents\" data-id=\"23b8341\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;headings_by_tags&quot;:[&quot;h2&quot;],&quot;exclude_headings_by_selector&quot;:[],&quot;no_headings_message&quot;:&quot;No headings were found on this page.&quot;,&quot;marker_view&quot;:&quot;numbers&quot;,&quot;minimize_box&quot;:&quot;yes&quot;,&quot;minimized_on&quot;:&quot;tablet&quot;,&quot;hierarchical_view&quot;:&quot;yes&quot;,&quot;min_height&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;min_height_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;min_height_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"table-of-contents.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-toc__header\">\n\t\t\t\t\t\t<h4 class=\"elementor-toc__header-title\">\n\t\t\t\t\u041f\u0440\u0435\u0441\u043a\u043e\u0447\u0438 \u0434\u043e:\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-toc__toggle-button elementor-toc__toggle-button--expand\" role=\"button\" tabindex=\"0\" aria-controls=\"elementor-toc__23b8341\" aria-expanded=\"true\" aria-label=\"Open table of contents\"><i aria-hidden=\"true\" class=\"fas fa-chevron-down\"><\/i><\/div>\n\t\t\t\t<div class=\"elementor-toc__toggle-button elementor-toc__toggle-button--collapse\" role=\"button\" tabindex=\"0\" aria-controls=\"elementor-toc__23b8341\" aria-expanded=\"true\" aria-label=\"Close table of contents\"><i aria-hidden=\"true\" class=\"fas fa-chevron-up\"><\/i><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<div id=\"elementor-toc__23b8341\" class=\"elementor-toc__body\">\n\t\t\t<div class=\"elementor-toc__spinner-container\">\n\t\t\t\t<i class=\"elementor-toc__spinner eicon-animation-spin eicon-loading\" aria-hidden=\"true\"><\/i>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-31f59e70 elementor-widget elementor-widget-text-editor\" data-id=\"31f59e70\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p id=\"docs-internal-guid-cf1cb398-7fff-f2e0-a021-c40c1f3efb31\" dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 (Saxenda) \u0435 \u043c\u0435\u0434\u0438\u043a\u0430\u043c\u0435\u043d\u0442 <\/span><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: bold; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u043f\u043e \u043b\u0435\u043a\u0430\u0440\u0441\u043a\u043e \u043f\u0440\u0435\u0434\u043f\u0438\u0441\u0430\u043d\u0438\u0435 <\/span><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0441\u044a\u0434\u044a\u0440\u0436\u0430\u0449 \u043f\u0435\u043f\u0442\u0438\u0434 \u043d\u0430\u0440\u0435\u0447\u0435\u043d \u043b\u0438\u0440\u0430\u0433\u043b\u0443\u0442\u0438\u0434. \u041b\u0438\u0440\u0430\u0433\u043b\u0443\u0442\u0438\u0434 \u0438\u043c\u0438\u0442\u0438\u0440\u0430 \u0444\u0443\u043d\u043a\u0446\u0438\u044f\u0442\u0430 \u043d\u0430 \u0435\u0441\u0442\u0435\u0441\u0442\u0432\u0435\u043d\u0438\u044f \u0438\u043d\u043a\u0440\u0435\u0442\u0438\u043d\u043e\u0432 \u0445\u043e\u0440\u043c\u043e\u043d \u043d\u0430\u0440\u0435\u0447\u0435\u043d \u0433\u043b\u044e\u043a\u0430\u0433\u043e\u043d\u043e\u043f\u043e\u0434\u043e\u0431\u0435\u043d \u043f\u0435\u043f\u0442\u0438\u0434-1 (GLP-1).<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0412 \u0440\u0435\u0437\u0443\u043b\u0442\u0430\u0442 \u043d\u0430 \u0442\u043e\u0432\u0430 \u0442\u043e\u0439 \u043e\u043a\u0430\u0437\u0432\u0430 \u0440\u0430\u0437\u043d\u043e\u043e\u0431\u0440\u0430\u0437\u043d\u0438 \u0435\u0444\u0435\u043a\u0442\u0438 \u0432\u044a\u0440\u0445\u0443 \u043e\u0440\u0433\u0430\u043d\u0438\u0437\u043c\u0430 \u0438 \u0435 \u043e\u0434\u043e\u0431\u0440\u0435\u043d \u043e\u0442 \u0415\u0432\u0440\u043e\u043f\u0435\u0439\u0441\u043a\u0430\u0442\u0430 \u041c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0430 \u0410\u0441\u043e\u0446\u0438\u0430\u0446\u0438\u044f (\u0415\u041c\u0410) \u0437\u0430 \u0448\u0438\u0440\u043e\u043a \u0441\u043f\u0435\u043a\u0442\u044a\u0440 \u043e\u0442 \u0441\u044a\u0441\u0442\u043e\u044f\u043d\u0438\u044f:<\/span><\/p><ul><li><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041a\u043e\u043d\u0442\u0440\u043e\u043b \u043d\u0430 \u043a\u0440\u044a\u0432\u043d\u0430\u0442\u0430 \u0437\u0430\u0445\u0430\u0440 \u043f\u0440\u0438 \u043f\u0440\u0438 \u0442\u0438\u043f 2 \u0434\u0438\u0430\u0431\u0435\u0442 (\u04222\u0414)<\/span><\/li><li><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041d\u0430\u043c\u0430\u043b\u044f\u0432\u0430\u043d\u0435 \u043d\u0430 \u0441\u044a\u0440\u0434\u0435\u0447\u043d\u043e\u0441\u044a\u0434\u043e\u0432\u0438\u044f \u0440\u0438\u0441\u043a \u043f\u0440\u0438 \u04222\u0414<\/span><\/li><li><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0423\u043f\u0440\u0430\u0432\u043b\u0435\u043d\u0438\u0435 \u043d\u0430 \u0442\u0435\u0433\u043b\u043e\u0442\u043e \u043f\u0440\u0438 \u044e\u043d\u043e\u0448\u0438 \u0438 \u0432\u044a\u0437\u0440\u0430\u0441\u0442\u043d\u0438<\/span><\/li><\/ul><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0412 \u0442\u0430\u0437\u0438 \u0441\u0442\u0430\u0442\u0438\u044f \u0449\u0435 \u0441\u0435 \u0437\u0430\u043f\u043e\u0437\u043d\u0430\u0435\u0442\u0435 \u0441 \u043f\u043e\u0434\u0440\u043e\u0431\u043d\u0430 \u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0446\u0438\u044f \u0437\u0430 \u043f\u043e\u043b\u0437\u0438\u0442\u0435, \u0440\u0438\u0441\u043a\u043e\u0432\u0435\u0442\u0435, \u0434\u043e\u0437\u0438\u0440\u0430\u043d\u0435\u0442\u043e \u0438 \u043f\u0440\u0438\u043b\u0430\u0433\u0430\u043d\u0435\u0442\u043e \u043d\u0430 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430.<\/span><\/p><h2><span style=\"font-size: 16pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041a\u0430\u043a\u0432\u043e \u0435 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430?<\/span><\/h2><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 (\u0442\u044a\u0440\u0433\u043e\u0432\u0441\u043a\u043e \u0438\u043c\u0435 \u043d\u0430 \u043f\u0435\u043f\u0442\u0438\u0434\u0430 <strong>\u043b\u0438\u0440\u0430\u0433\u043b\u0443\u0442\u0438\u0434<\/strong>) \u0435 \u0441\u0438\u043d\u0442\u0435\u0442\u0438\u0447\u0435\u043d \u043f\u0435\u043f\u0442\u0438\u0434, \u0440\u0430\u0437\u0440\u0430\u0431\u043e\u0442\u0435\u043d \u043e\u0442 \u0434\u0430\u0442\u0441\u043a\u0430\u0442\u0430 \u0444\u0430\u0440\u043c\u0430\u0446\u0435\u0432\u0442\u0438\u0447\u043d\u0430 \u043a\u043e\u043c\u043f\u0430\u043d\u0438\u044f \u041d\u043e\u0432\u043e \u041d\u043e\u0440\u0434\u0438\u0441\u043a (Novo Nordisk) \u043f\u0440\u0435\u0437 1990 \u0433.\u00a0<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041f\u0435\u043f\u0442\u0438\u0434\u0438\u0442\u0435 \u0441\u0430 \u0432\u0435\u0449\u0435\u0441\u0442\u0432\u0430 \u0438\u0437\u0433\u0440\u0430\u0434\u0435\u043d\u0438 \u043e\u0442 \u0430\u043c\u0438\u043d\u043e\u043a\u0438\u0441\u0435\u043b\u0438\u043d\u0438 (\u043a\u0430\u043a\u0442\u043e \u0431\u0435\u043b\u0442\u044a\u0447\u0438\u043d\u0438\u0442\u0435) \u043a\u043e\u0438\u0442\u043e \u0441\u0435 \u0441\u0440\u0435\u0449\u0430\u0442 \u0435\u0441\u0442\u0432\u0435\u043d\u043e \u0432\u044a\u0432 \u0432\u0441\u0438\u0447\u043a\u0438 \u0436\u0438\u0432\u0438 \u043e\u0440\u0433\u0430\u043d\u0438\u0437\u043c\u0438, \u0432\u043a\u043b. \u0447\u043e\u0432\u0435\u043a\u0430.<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0435 \u0440\u0430\u0437\u0440\u0430\u0431\u043e\u0442\u0435\u043d \u043a\u0430\u0442\u043e \u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u043e \u0437\u0430 \u043a\u043e\u043d\u0442\u0440\u043e\u043b \u043d\u0430 \u043a\u0440\u044a\u0432\u043d\u0430\u0442\u0430 \u0437\u0430\u0445\u0430\u0440 \u0438 \u0430\u043f\u0435\u0442\u0438\u0442\u0430, \u043a\u043e\u0435\u0442\u043e \u0438\u043c\u0438\u0442\u0438\u0440\u0430 \u0435\u0441\u0442\u0435\u0441\u0442\u0432\u0435\u043d\u043e \u043f\u0440\u043e\u0434\u0443\u0446\u0438\u0440\u0430\u0449\u0438\u044f \u0441\u0435 \u0432 \u0447\u043e\u0432\u0435\u0448\u043a\u043e\u0442\u043e \u0442\u044f\u043b\u043e \u0445\u043e\u0440\u043c\u043e\u043d GLP-1, \u043d\u043e \u0438\u043c\u0430 \u043f\u043e-\u0434\u044a\u043b\u044a\u0433 \u043f\u043e\u043b\u0443\u0436\u0438\u0432\u043e\u0442 \u043f\u0440\u0438 \u043f\u043e\u043f\u0430\u0434\u0430\u043d\u0435\u0442\u043e \u043c\u0443 \u0432 \u043e\u0440\u0433\u0430\u043d\u0438\u0437\u043c\u0430 [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6474072\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">1<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].\u00a0<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0438\u043c\u0430 97% \u0438\u0434\u0435\u043d\u0442\u0438\u0447\u043d\u0430 \u0441\u0442\u0440\u0443\u043a\u0442\u0443\u0440\u0430 \u0441 \u0435\u0441\u0442\u0435\u0441\u0442\u0432\u0435\u043d\u0438\u044f GLP-1 [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21517658\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">2<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">]. \u0422\u0440\u0438\u0442\u0435 \u043f\u0440\u043e\u0446\u0435\u043d\u0442\u0430 \u0440\u0430\u0437\u043b\u0438\u043a\u0430 \u0438\u0434\u0432\u0430\u0442 \u043e\u0442 2 \u043e\u0441\u043d\u043e\u0432\u043d\u0438 \u043c\u043e\u0434\u0438\u0444\u0438\u043a\u0430\u0446\u0438\u0438:\u00a0<\/span><\/p><ul><li><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0414\u043e\u0431\u0430\u0432\u044f\u043d\u0435 \u043d\u0430 \u043c\u0430\u0441\u0442\u043d\u0430 \u043a\u0438\u0441\u0435\u043b\u0438\u043d\u0430 (\u043f\u0430\u043b\u043c\u0438\u0442\u0430\u0442) \u043a\u044a\u043c \u0430\u043c\u0438\u043d\u043e\u043a\u0438\u0441\u0435\u043b\u0438\u043d\u0430\u0442\u0430 \u043b\u0438\u0437\u0438\u043d \u043d\u0430 26-\u0442\u0430 \u043f\u043e\u0437\u0438\u0446\u0438\u044f \u0432 GLP-1, \u043a\u043e\u0435\u0442\u043e \u0441\u043f\u043e\u043c\u0430\u0433\u0430 \u0437\u0430 \u0437\u0430\u0431\u0430\u0432\u044f\u043d\u0435 \u043d\u0430 \u0431\u044a\u0431\u0440\u0435\u0447\u043d\u0430\u0442\u0430 \u0435\u043a\u0441\u043a\u0440\u0435\u0446\u0438\u044f \u043f\u043e\u0440\u0430\u0434\u0438 \u0441\u0432\u044a\u0440\u0437\u0432\u0430\u043d\u0435 \u0441\u044a\u0441 \u0441\u0435\u0440\u0443\u043c\u043d\u0438\u044f \u0430\u043b\u0431\u0443\u043c\u0438\u043d.<\/span><\/span><\/span><\/span><\/span><\/span><\/li><li><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0410\u043c\u0438\u043d\u043e\u043a\u0438\u0441\u0435\u043b\u043d\u0430\u0442\u0430 \u043b\u0438\u0437\u0438\u043d \u0435 \u0437\u0430\u043c\u0435\u043d\u0435\u043d\u0430 \u0441 \u0430\u0440\u0433\u0438\u043d\u0438\u043d \u043d\u0430 \u043f\u043e\u0437\u0438\u0446\u0438\u044f 34 \u0432 \u0435\u0441\u0442\u0435\u0441\u0442\u0432\u0435\u043d\u0438\u044f GLP-1 \u043a\u043e\u0435\u0442\u043e \u0434\u043e\u043f\u044a\u043b\u043d\u0438\u0442\u0435 \u0443\u0432\u0435\u043b\u0438\u0447\u0430\u0432\u0430 \u0441\u0442\u0430\u0431\u0438\u043b\u043d\u043e\u0441\u0442\u0442\u0430 \u043d\u0430 \u043f\u0435\u043f\u0442\u0438\u0434\u0430.<\/span><\/li><\/ul><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0422\u0435\u0437\u0438 \u043c\u043e\u0434\u0438\u0444\u0438\u043a\u0430\u0446\u0438\u0438 \u0441\u043f\u043e\u043c\u0430\u0433\u0430\u0442 \u0437\u0430 \u0443\u0432\u0435\u043b\u0438\u0447\u0430\u0432\u0430\u043d\u0435 \u043d\u0430 \u043f\u043e\u043b\u0443\u0436\u0438\u0432\u043e\u0442\u0430 (\u0432\u0440\u0435\u043c\u0435\u0442\u043e \u0437\u0430 \u043a\u043e\u0435\u0442\u043e \u0441\u0435 \u0437\u0430\u0434\u044a\u0440\u0436\u0430 \u0432 \u043e\u0440\u0433\u0430\u043d\u0438\u0437\u043c\u0430) \u043d\u0430 \u043f\u0435\u043f\u0442\u0438\u0434\u0430 \u0441 \u0434\u043e 13 \u0447\u0430\u0441\u0430, \u043a\u043e\u0435\u0442\u043e \u043f\u043e\u0437\u0432\u043e\u043b\u044f\u0432\u0430 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0434\u0430 \u0435 \u0435\u0444\u0435\u043a\u0442\u0438\u0432\u0435\u043d \u0434\u043e\u0440\u0438 \u043f\u0440\u0438 \u0434\u043e\u0437\u0438\u0440\u0430\u043d\u0435 \u0441\u0430\u043c\u043e \u0432\u0435\u0434\u043d\u044a\u0436 \u043d\u0430 \u0434\u0435\u043d [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7088919\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">3<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0415\u041c\u0410 \u043f\u043e\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u0442\u0435\u043b\u043d\u043e \u043e\u0434\u043e\u0431\u0440\u044f\u0432\u0430 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0437\u0430 \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0430 \u0443\u043f\u043e\u0442\u0440\u0435\u0431\u0430 \u043f\u0440\u0438 \u0445\u043e\u0440\u0430 \u0441 \u0440\u0430\u0437\u043b\u0438\u0447\u043d\u0438 \u0437\u0430\u0431\u043e\u043b\u044f\u0432\u0430\u043d\u0438\u044f:<\/span><\/p><ul><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041b\u0438\u0440\u0430\u0433\u043b\u0443\u0442\u0438\u0434 (\u0441\u044a\u0441\u0442\u0430\u0432\u043a\u0430\u0442\u0430 \u043d\u0430 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430) \u043f\u043e\u043b\u0443\u0447\u0430\u0432\u0430 \u043f\u044a\u0440\u0432\u043e\u0442\u043e \u0441\u0438 \u043e\u0434\u043e\u0431\u0440\u0435\u043d\u0438\u0435 \u043e\u0442 \u0415\u041c\u0410 \u043f\u0440\u0435\u0437 2009 \u0433. \u0437\u0430 \u043b\u0435\u0447\u0435\u043d\u0438\u0435 \u043d\u0430 \u0434\u0438\u0430\u0431\u0435\u0442 \u0442\u0438\u043f 2 (\u04222\u0414) [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7878668\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">4<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">]. \u041f\u043e-\u043a\u043e\u043d\u043a\u0440\u0435\u0442\u043d\u043e, \u043f\u0435\u043f\u0442\u0438\u0434\u044a\u0442 \u0435 \u043e\u0434\u043e\u0431\u0440\u0435\u043d \u043a\u0430\u0442\u043e \u043f\u043e\u0434\u043a\u043e\u0436\u043d\u0430 \u0438\u043d\u0436\u0435\u043a\u0446\u0438\u044f \u0432 \u0434\u043e\u0437\u0430 \u0434\u043e 1,8 \u043c\u0433\/\u0434\u0435\u043d \u043f\u043e\u0434 \u0442\u044a\u0440\u0433\u043e\u0432\u0441\u043a\u043e\u0442\u043e \u043d\u0430\u0438\u043c\u0435\u043d\u043e\u0432\u0430\u043d\u0438\u0435 \u0412\u0438\u043a\u0442\u043e\u0437\u0430 (Victoza).<br \/><\/span><\/span><\/span><\/span><\/span><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0412\u0438\u043a\u0442\u043e\u0437\u0430 \u0435 \u043e\u0434\u043e\u0431\u0440\u0435\u043d\u0430 \u0438 \u0437\u0430 \u043d\u0430\u043c\u0430\u043b\u044f\u0432\u0430\u043d\u0435 \u043d\u0430 \u0440\u0438\u0441\u043a\u0430 \u043e\u0442 \u0441\u044a\u0440\u0434\u0435\u0447\u043d\u043e\u0441\u044a\u0434\u043e\u0432\u0438 \u0438\u043d\u0446\u0438\u0434\u0435\u043d\u0442\u0438 \u043f\u0440\u0438 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0438 \u0441 \u04222\u0414 [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.ema.europa.eu\/en\/medicines\/human\/EPAR\/victoza\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">5<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].<\/span><\/span><\/span><\/span><\/span><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041f\u0440\u0435\u0437 2015 \u0433. \u043b\u0438\u0440\u0430\u0433\u043b\u0443\u0442\u0438\u0434 \u0441 \u0442\u044a\u0440\u0433\u043e\u0432\u0441\u043a\u043e\u0442\u043e \u0438\u043c\u0435 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0435 \u043e\u0434\u043e\u0431\u0440\u0435\u043d \u0438 \u0432 \u043f\u043e-\u0432\u0438\u0441\u043e\u043a\u0430 \u0434\u043e\u0437\u0430 \u043e\u0442 3 \u043c\u0433\/\u0434\u0435\u043d \u0437\u0430 \u043b\u0435\u0447\u0435\u043d\u0438\u0435 \u043d\u0430 \u0432\u044a\u0437\u0440\u0430\u0441\u0442\u043d\u0438 \u0441 \u043d\u0430\u0434\u043d\u043e\u0440\u043c\u0435\u043d\u043e \u0442\u0435\u0433\u043b\u043e (\u0438 \u043f\u043e\u043d\u0435 \u0435\u0434\u043d\u043e \u0437\u0430\u0431\u043e\u043b\u044f\u0432\u0430\u043d\u0435 \u0441\u0432\u044a\u0440\u0437\u0430\u043d\u043e \u0441 \u043d\u0430\u0434\u043d\u043e\u0440\u043c\u0435\u043d\u043e\u0442\u043e \u0442\u0435\u0433\u043b\u043e &#8211; \u0432\u0438\u0441\u043e\u043a\u043e \u043a\u0440\u044a\u0432\u043d\u043e, \u043f\u043e\u0434\u0430\u0433\u0440\u0430 \u0438 \u0442.\u043d.) \u0438\u043b\u0438 \u0437\u0430\u0442\u043b\u044a\u0441\u0442\u044f\u0432\u0430\u043d\u0435 [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26074046\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">6<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].<\/span><\/span><\/span><\/span><\/span><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041f\u0440\u0435\u0437 2021 \u0433. \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u043f\u043e\u043b\u0443\u0447\u0438 \u043e\u0434\u043e\u0431\u0440\u0435\u043d\u0438\u0435 \u0438 \u0437\u0430 \u0443\u043f\u043e\u0442\u0440\u0435\u0431\u0430 \u043f\u0440\u0438 \u044e\u043d\u043e\u0448\u0438 \u0441 \u043d\u0430\u0434\u043d\u043e\u0440\u043c\u0435\u043d\u043e \u0442\u0435\u0433\u043b\u043e \u0438\u043b\u0438 \u0437\u0430\u0442\u043b\u044a\u0441\u0442\u044f\u0432\u0430\u043d\u0435 [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.ema.europa.eu\/en\/medicines\/human\/EPAR\/saxenda\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">7<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].<\/span><\/li><\/ul><h2 dir=\"ltr\" style=\"line-height: 1.38; margin-top: 18pt; margin-bottom: 6pt;\"><span style=\"font-size: 16pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0420\u0430\u0431\u043e\u0442\u0438 \u043b\u0438 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430? \u041e\u0441\u043d\u043e\u0432\u043d\u0438 \u041c\u0435\u0445\u0430\u043d\u0438\u0437\u043c\u0438<\/span><\/h2><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0440\u0430\u0431\u043e\u0442\u0438, \u043a\u0430\u0442\u043e \u0438\u043c\u0438\u0442\u0438\u0440\u0430 \u0434\u0435\u0439\u0441\u0442\u0432\u0438\u0435\u0442\u043e \u043d\u0430 GLP-1 \u0438 \u0430\u043a\u0442\u0438\u0432\u0438\u0440\u0430 \u043d\u0435\u0433\u043e\u0432\u0438\u0442\u0435 \u0440\u0435\u0446\u0435\u043f\u0442\u043e\u0440\u0438 \u0432 \u0440\u0430\u0437\u043b\u0438\u0447\u043d\u0438 \u043e\u0440\u0433\u0430\u043d\u0438:<\/span><\/p><ul><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041f\u0430\u043d\u043a\u0440\u0435\u0430\u0441 &#8211; \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0441\u0442\u0438\u043c\u0443\u043b\u0438\u0440\u0430 \u0441\u0435\u043a\u0440\u0435\u0446\u0438\u044f\u0442\u0430 \u043d\u0430 \u0438\u043d\u0441\u0443\u043b\u0438\u043d, \u043a\u0430\u0442\u043e \u0430\u043a\u0442\u0438\u0432\u0438\u0440\u0430 \u0431\u0435\u0442\u0430-\u043a\u043b\u0435\u0442\u043a\u0438\u0442\u0435 \u0432 \u043f\u0430\u043d\u043a\u0440\u0435\u0430\u0441\u0430 \u0438 \u0438\u043d\u0445\u0438\u0431\u0438\u0440\u0430 \u0441\u0435\u043a\u0440\u0435\u0446\u0438\u044f\u0442\u0430 \u043d\u0430 \u0433\u043b\u044e\u043a\u0430\u0433\u043e\u043d \u043e\u0442 \u0430\u043b\u0444\u0430-\u043a\u043b\u0435\u0442\u043a\u0438\u0442\u0435. \u0422\u043e\u0432\u0430 \u0433\u043e \u043f\u0440\u0430\u0432\u0438 \u0438\u0437\u043a\u043b\u044e\u0447\u0438\u0442\u0435\u043b\u043d\u043e \u0435\u0444\u0435\u043a\u0442\u0438\u0432\u0435\u043d \u0437\u0430 \u043a\u043e\u043d\u0442\u0440\u043e\u043b\u0438\u0440\u0430\u043d\u0435 \u043d\u0430 \u043a\u0440\u044a\u0432\u043d\u0430\u0442\u0430 \u0437\u0430\u0445\u0430\u0440 \u043f\u0440\u0438 \u04222\u0414 [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29225111\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">8<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].<\/span><\/span><\/span><\/span><\/span><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0425\u0440\u0430\u043d\u043e\u0441\u043c\u0438\u043b\u0430\u0442\u0435\u043b\u043d\u0430 \u0441\u0438\u0441\u0442\u0435\u043c\u0430 &#8211; \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u043c\u043e\u0436\u0435 \u0434\u0430 \u0437\u0430\u0431\u0430\u0432\u0438 \u0438\u0437\u043f\u0440\u0430\u0437\u0432\u0430\u043d\u0435\u0442\u043e \u043d\u0430 \u0441\u0442\u043e\u043c\u0430\u0445\u0430, \u043a\u043e\u0435\u0442\u043e \u043d\u0430\u043c\u0430\u043b\u044f\u0432\u0430 \u043d\u0430 \u0441\u043a\u043e\u043a\u0430 \u043d\u0430 \u0433\u043b\u044e\u043a\u043e\u0437\u0430\u0442\u0430 \u0441\u043b\u0435\u0434 \u0445\u0440\u0430\u043d\u0435\u043d\u0435. \u041f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0438\u044f\u0442\u0430 \u0441 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0432 \u0434\u043e\u0437\u0430 3 \u043c\u0433\/\u0434\u0435\u043d \u043f\u043e\u043a\u0430\u0437\u0432\u0430\u0442 23% \u043d\u0430\u043c\u0430\u043b\u0435\u043d\u0438\u0435 \u043d\u0430 \u0441\u043a\u043e\u0440\u043e\u0441\u0442\u0442\u0430 \u043d\u0430 \u0438\u0437\u043f\u0440\u0430\u0437\u0432\u0430\u043d\u0435 \u043d\u0430 \u0441\u0442\u043e\u043c\u0430\u0445\u0430 \u0432 \u0440\u0430\u043c\u043a\u0438\u0442\u0435 \u043d\u0430 \u043f\u044a\u0440\u0432\u0438\u044f \u0447\u0430\u0441 \u0441\u043b\u0435\u0434 \u043a\u043e\u043d\u0441\u0443\u043c\u0430\u0446\u0438\u044f \u043d\u0430 \u0445\u0440\u0430\u043d\u0430 [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4052428\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">9<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].<\/span><\/span><\/span><\/span><\/span><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041c\u0430\u0441\u0442\u043d\u0430\u0442\u0430 \u0442\u044a\u043a\u0430\u043d &#8211; \u0412\u0437\u0430\u0438\u043c\u043e\u0434\u0435\u0439\u0441\u0442\u0432\u0430\u0439\u043a\u0438 \u0441 GLP-1 \u0440\u0435\u0446\u0435\u043f\u0442\u043e\u0440\u0438\u0442\u0435 \u0432 \u043c\u0430\u0441\u0442\u043d\u0430\u0442\u0430 \u0442\u044a\u043a\u0430\u043d, \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u043c\u043e\u0436\u0435 \u0434\u0430 \u043d\u0430\u043c\u0430\u043b\u0438 \u043e\u0441\u0432\u043e\u0431\u043e\u0436\u0434\u0430\u0432\u0430\u043d\u0435\u0442\u043e \u043d\u0430 \u0442\u0440\u0438\u0433\u043b\u0438\u0446\u0435\u0440\u0438\u0434\u0438 \u0432 \u043a\u0440\u044a\u0432\u0442\u0430 \u0438 \u0434\u0430 \u043f\u043e\u0434\u043e\u0431\u0440\u0438 \u0438\u043d\u0441\u0443\u043b\u0438\u043d\u043e\u0432\u0430\u0442\u0430 \u0447\u0443\u0432\u0441\u0442\u0432\u0438\u0442\u0435\u043b\u043d\u043e\u0441\u0442 [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6472499\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">10<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].<\/span><\/span><\/span><\/span><\/span><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041c\u043e\u0437\u044a\u043a &#8211; \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0430\u043a\u0442\u0438\u0432\u0438\u0440\u0430 GLP-1 \u0440\u0435\u0446\u0435\u043f\u0442\u043e\u0440\u0438\u0442\u0435 \u0432 \u0446\u0435\u043d\u0442\u0440\u0430\u043b\u043d\u0430\u0442\u0430 \u043d\u0435\u0440\u0432\u043d\u0430 \u0441\u0438\u0441\u0442\u0435\u043c\u0430, \u043a\u043e\u0435\u0442\u043e \u0432\u043e\u0434\u0438 \u0434\u043e \u043d\u0430\u043c\u0430\u043b\u044f\u0432\u0430\u043d\u0435 \u043d\u0430 \u0430\u043f\u0435\u0442\u0438\u0442\u0430 \u0438 \u0438\u0433\u0440\u0430\u0435 \u043a\u043b\u044e\u0447\u043e\u0432\u0430 \u0440\u043e\u043b\u044f \u0437\u0430 \u0435\u0444\u0435\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u0442\u0430 \u043c\u0443 \u0437\u0430 \u0437\u0430\u0433\u0443\u0431\u0430\u0442\u0430 \u043d\u0430 \u0442\u0435\u0433\u043b\u043e \u043f\u0440\u0438 \u0445\u043e\u0440\u0430 \u0441 \u043d\u0430\u0434\u043d\u043e\u0440\u043c\u0435\u043d\u043e \u0442\u0435\u0433\u043b\u043e \u0438 \u0437\u0430\u0442\u043b\u044a\u0441\u0442\u044f\u0432\u0430\u043d\u0435 [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3594872\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">11<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">, <\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3280675\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">12<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].<\/span><\/li><\/ul><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0421\u043c\u044f\u0442\u0430 \u0441\u0435, \u0447\u0435 \u043a\u0430\u0442\u043e \u0432\u0437\u0430\u0438\u043c\u043e\u0434\u0435\u0439\u0441\u0442\u0432\u0430 \u0441 GLP-1 \u0440\u0435\u0446\u0435\u043f\u0442\u043e\u0440\u0438\u0442\u0435 \u0432 \u043c\u043e\u0437\u044a\u043a\u0430, \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u043e\u0441\u0438\u0433\u0443\u0440\u044f\u0432\u0430 \u0438 \u043d\u0435\u0432\u0440\u043e\u043f\u0440\u043e\u0442\u0435\u043a\u0442\u0438\u0432\u043d\u0438 \u043f\u043e\u043b\u0437\u0438, \u0432\u044a\u043f\u0440\u0435\u043a\u0438 \u0447\u0435 \u043f\u0435\u043f\u0442\u0438\u0434\u044a\u0442 \u0432\u0441\u0435 \u043e\u0449\u0435 \u0441\u0435 \u0438\u0437\u0441\u043b\u0435\u0434\u0432\u0430 \u0437\u0430 \u043f\u043e\u0442\u0435\u043d\u0446\u0438\u0430\u043b\u0430 \u043c\u0443 \u0441\u0440\u0435\u0449\u0443 \u043d\u0435\u0432\u0440\u043e\u0434\u0435\u0433\u0435\u043d\u0435\u0440\u0430\u0442\u0438\u0432\u043d\u0438 \u0441\u044a\u0441\u0442\u043e\u044f\u043d\u0438\u044f [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6429395\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">13<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041e\u0441\u0432\u0435\u043d \u0442\u043e\u0432\u0430 \u0432 \u043c\u043e\u043c\u0435\u043d\u0442\u0430 \u0441\u0435 \u043f\u0440\u043e\u0432\u0435\u0436\u0434\u0430\u0442 \u0438\u0437\u0441\u043b\u0435\u0434\u0432\u0430\u043d\u0438\u044f \u0437\u0430 \u043f\u043e\u0442\u0435\u043d\u0446\u0438\u0430\u043b\u043d\u0438\u0442\u0435 \u0435\u0444\u0435\u043a\u0442\u0438 \u043d\u0430 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0432\u044a\u0440\u0445\u0443 \u0441\u044a\u0441\u0442\u043e\u044f\u043d\u0438\u044f, \u0441\u0432\u044a\u0440\u0437\u0430\u043d\u0438 \u0441\u044a\u0441 \u0437\u0430\u0442\u043b\u044a\u0441\u0442\u044f\u0432\u0430\u043d\u0435\u0442\u043e, \u043a\u0430\u0442\u043e \u0441\u0438\u043d\u0434\u0440\u043e\u043c \u043d\u0430 \u043f\u043e\u043b\u0438\u043a\u0438\u0441\u0442\u043e\u0437\u043d\u0438\u0442\u0435 \u044f\u0439\u0447\u043d\u0438\u0446\u0438 (\u041f\u041a\u042f) \u0438 \u043e\u043c\u0430\u0437\u043d\u0435\u043d \u0447\u0435\u0440\u0435\u043d \u0434\u0440\u043e\u0431 (\u043d\u0435\u0430\u043b\u043a\u043e\u0445\u043e\u043b\u043d\u0430 \u043c\u0430\u0441\u0442\u043d\u0430 \u0447\u0435\u0440\u043d\u043e\u0434\u0440\u043e\u0431\u043d\u0430 \u0431\u043e\u043b\u0435\u0441\u0442, \u041d\u0410\u041c\u0427\u0411) [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5424770\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">14<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">, <\/span><a style=\"text-decoration: none;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33309563\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">15<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].<\/span><\/p><p><img fetchpriority=\"high\" decoding=\"async\" class=\"size-full wp-image-5127\" src=\"https:\/\/drmarinov.com\/wp-content\/uploads\/2024\/02\/GLP-1-main.jpg\" alt=\"\u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0440\u0435\u0437\u0443\u043b\u0442\u0430\u0442\u0438\" width=\"1200\" height=\"772\" srcset=\"https:\/\/drmarinov.com\/wp-content\/uploads\/2024\/02\/GLP-1-main.jpg 1200w, https:\/\/drmarinov.com\/wp-content\/uploads\/2024\/02\/GLP-1-main-300x193.jpg 300w, https:\/\/drmarinov.com\/wp-content\/uploads\/2024\/02\/GLP-1-main-1024x659.jpg 1024w, https:\/\/drmarinov.com\/wp-content\/uploads\/2024\/02\/GLP-1-main-768x494.jpg 768w, https:\/\/drmarinov.com\/wp-content\/uploads\/2024\/02\/GLP-1-main-18x12.jpg 18w\" sizes=\"(max-width: 1200px) 100vw, 1200px\" \/><\/p><h2 dir=\"ltr\" style=\"line-height: 1.3800000000000001; margin-top: 18pt; margin-bottom: 6pt;\"><span style=\"font-size: 16pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0420\u0435\u0437\u0443\u043b\u0442\u0430\u0442\u0438 \u043e\u0442 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 | \u041d\u0430\u0439-\u043d\u043e\u0432\u0438 \u041d\u0430\u0443\u0447\u043d\u0438 \u0414\u0430\u043d\u043d\u0438<\/span><\/h2><p dir=\"ltr\" style=\"line-height: 1.3800000000000001; margin-top: 12pt; margin-bottom: 12pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0414\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u0441\u0442\u0432\u0430\u0442\u0430 \u0441\u043e\u0447\u0430\u0442, \u0447\u0435 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u043f\u0440\u0435\u0434\u043b\u0430\u0433\u0430 \u0448\u0438\u0440\u043e\u043a \u0441\u043f\u0435\u043a\u0442\u044a\u0440 \u043e\u0442 \u043f\u043e\u043b\u0437\u0438 \u0437\u0430 \u043a\u043e\u043d\u0442\u0440\u043e\u043b\u0430 \u043d\u0430 \u0442\u0435\u0433\u043b\u043e\u0442\u043e, \u043c\u0435\u0442\u0430\u0431\u043e\u043b\u0438\u0437\u043c\u0430 \u0438 \u0441\u044a\u0440\u0434\u0435\u0447\u043d\u043e\u0441\u044a\u0434\u043e\u0432\u043e\u0442\u043e \u0437\u0434\u0440\u0430\u0432\u0435.\u00a0<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.3800000000000001; margin-top: 12pt; margin-bottom: 12pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041d\u044f\u043a\u043e\u0439 \u043e\u0442 \u043f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0438\u044f\u0442\u0430 \u0432\u043a\u043b\u044e\u0447\u0432\u0430\u0442 \u043f\u043e\u0447\u0442\u0438 4000 \u0443\u0447\u0430\u0441\u0442\u043d\u0438\u0446\u0438 \u0438 \u043f\u0440\u043e\u0434\u044a\u043b\u0436\u0430\u0432\u0430\u0442 \u043f\u043e\u0432\u0435\u0447\u0435 \u043e\u0442 \u0433\u043e\u0434\u0438\u043d\u0430. \u041d\u0430\u0439-\u0432\u0430\u0436\u043d\u0438\u0442\u0435 \u043e\u0442 \u0442\u044f\u0445 \u0449\u0435 \u043e\u0442\u043a\u0440\u0438\u0435\u0442\u0435 \u0432 \u0441\u043b\u0435\u0434\u0432\u0430\u0449\u0438\u0442\u0435 \u0440\u0435\u0434\u043e\u0432\u0435:<\/span><\/p><h3 dir=\"ltr\" style=\"line-height: 1.38; margin-top: 16pt; margin-bottom: 4pt;\"><span style=\"font-size: 13.999999999999998pt; font-family: Arial,sans-serif; color: #434343; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041f\u043e\u043d\u0438\u0436\u0430\u0432\u0430\u043d\u0435 \u043d\u0430 \u043d\u0430\u0434\u043d\u043e\u0440\u043c\u0435\u043d\u043e \u0442\u0435\u0433\u043b\u043e \u0441\u044a\u0441 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430\u00a0<\/span><\/h3><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0435 \u043e\u0434\u043e\u0431\u0440\u0435\u043d\u0430 \u0437\u0430 \u043f\u043e\u043d\u0438\u0436\u0430\u0432\u0430\u043d\u0435 \u043d\u0430 \u043d\u0430\u0434\u043d\u043e\u0440\u043c\u0435\u043d\u043e \u0442\u0435\u0433\u043b\u043e \u0438 \u043e\u0442\u0441\u043b\u0430\u0431\u0432\u0430\u043d\u0435 \u0441\u043b\u0435\u0434 \u043e\u0446\u0435\u043d\u043a\u0430 \u043d\u0430 \u0435\u0444\u0435\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442 \u0438 \u0431\u0435\u0437\u043e\u043f\u0430\u0441\u043d\u043e\u0441\u0442 \u0432 \u0442\u0440\u0438 \u0433\u043e\u043b\u0435\u043c\u0438 \u043a\u043b\u0438\u043d\u0438\u0447\u043d\u0438 \u043f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0438\u044f (\u0444\u0430\u0437\u0430 3), \u043a\u043e\u0438\u0442\u043e \u0441\u0430 \u0447\u0430\u0441\u0442 \u043e\u0442 \u043a\u043b\u0438\u043d\u0438\u0447\u043d\u0430\u0442\u0430 \u043f\u0440\u043e\u0433\u0440\u0430\u043c\u0430 \u043d\u0430 \u041d\u043e\u0432\u043e \u041d\u043e\u0440\u0434\u0438\u0441\u043a \u043d\u0430\u0440\u0435\u0447\u0435\u043d\u0430 SCALE (Satiety and Clinical Adiposity \u2013 Liraglutide Evidence in individuals with and without diabetes).<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0412 \u0442\u0435\u0437\u0438 \u0438\u0437\u043f\u0438\u0442\u0432\u0430\u043d\u0438\u044f, \u0432\u0441\u044f\u043a\u043e \u043e\u0442 \u043a\u043e\u0438\u0442\u043e \u043f\u0440\u043e\u0434\u044a\u043b\u0436\u0430\u0432\u0430 56 \u0441\u0435\u0434\u043c\u0438\u0446\u0438, \u0441\u0430 \u0443\u0447\u0430\u0441\u0442\u0432\u0430\u043b\u0438 \u043e\u0431\u0449\u043e \u043f\u043e\u0432\u0435\u0447\u0435 \u043e\u0442 5000 \u0443\u0447\u0430\u0441\u0442\u043d\u0438\u0446\u0438 \u0441 \u043d\u0430\u0434\u043d\u043e\u0440\u043c\u0435\u043d\u043e \u0442\u0435\u0433\u043b\u043e \u0438 \u0437\u0430\u0442\u043b\u044a\u0441\u0442\u044f\u0432\u0430\u043d\u0435, \u0441 \u0438 \u0431\u0435\u0437 \u04222\u0414.<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041f\u043e \u0432\u0440\u0435\u043c\u0435 \u043d\u0430 \u043f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0438\u044f\u0442\u0430 \u0443\u0447\u0430\u0441\u0442\u043d\u0438\u0446\u0438\u0442\u0435 \u0441\u0430 \u043f\u043e\u043b\u0443\u0447\u0430\u0432\u0430\u043b\u0438 \u0434\u043d\u0435\u0432\u043d\u0430 \u0434\u043e\u0437\u0430 \u043e\u0442 3 \u043c\u0433 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0438\u043b\u0438 \u043f\u043b\u0430\u0446\u0435\u0431\u043e, \u043a\u0430\u043a\u0442\u043e \u0438 \u0441\u044a\u0432\u0435\u0442\u0438 \u0437\u0430 \u0441\u043f\u0430\u0437\u0432\u0430\u043d\u0435 \u043d\u0430 \u043d\u0438\u0441\u043a\u043e\u043a\u0430\u043b\u043e\u0440\u0438\u0447\u043d\u0430 \u0434\u0438\u0435\u0442\u0430 \u0438 \u0440\u0435\u0434\u043e\u0432\u043d\u0438 \u0444\u0438\u0437\u0438\u0447\u0435\u0441\u043a\u0438 \u0443\u043f\u0440\u0430\u0436\u043d\u0435\u043d\u0438\u044f:<\/span><\/p><ul><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041f\u044a\u0440\u0432\u043e\u0442\u043e \u0438 \u043d\u0430\u0439-\u0433\u043e\u043b\u044f\u043c\u043e \u043f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0435 \u0432\u043a\u043b\u044e\u0447\u0432\u0430 3731 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0438 \u0431\u0435\u0437 \u04222\u0414 \u0438 \u0438\u043d\u0434\u0435\u043a\u0441 \u043d\u0430 \u0442\u0435\u043b\u0435\u0441\u043d\u0430 \u043c\u0430\u0441\u0430 (\u0418\u0422\u041c) \u043d\u0430\u0434 27 \u043a\u0433\/\u043c<\/span><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 0.6em; vertical-align: super;\">2<\/span><\/span><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">. \u0421\u043b\u0435\u0434 56 \u0441\u0435\u0434\u043c\u0438\u0446\u0438 \u0443\u0447\u0430\u0441\u0442\u043d\u0438\u0446\u0438\u0442\u0435, \u043a\u043e\u0438\u0442\u043e \u0441\u0430 \u043f\u043e\u043b\u0443\u0447\u0430\u0432\u0430\u043b\u0438 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 (\u0437\u0430\u0435\u0434\u043d\u043e \u0441 \u0434\u0438\u0435\u0442\u0430), \u0441\u0432\u0430\u043b\u044f\u0442 \u043e\u043a\u043e\u043b\u043e 8.4 \u043a\u0433 (\u043e\u043a\u043e\u043b\u043e 8% \u043e\u0442 \u0438\u0437\u0445\u043e\u0434\u043d\u043e\u0442\u043e \u043d\u0438\u0432\u043e), \u0434\u043e\u043a\u0430\u0442\u043e \u0442\u0435\u0437\u0438 \u0432 \u0433\u0440\u0443\u043f\u0430\u0442\u0430 \u043d\u0430 \u043f\u043b\u0430\u0446\u0435\u0431\u043e (\u0437\u0430\u0435\u0434\u043d\u043e \u0441 \u0434\u0438\u0435\u0442\u0430) \u0441\u0430 \u0437\u0430\u0433\u0443\u0431\u0438\u043b\u0438 2.8 \u043a\u0433 (\u0441\u0440\u0435\u0434\u043d\u043e) [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26132939\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">16<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].<\/span><\/span><\/span><\/span><\/span><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0412\u0442\u043e\u0440\u043e\u0442\u043e \u043f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0435 \u0432\u043a\u043b\u044e\u0447\u0432\u0430 846 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0438 \u0441 \u043d\u0430\u0434\u043d\u043e\u0440\u043c\u0435\u043d\u043e \u0442\u0435\u0433\u043b\u043e \u0438\u043b\u0438 \u0437\u0430\u0442\u043b\u044a\u0441\u0442\u044f\u0432\u0430\u043d\u0435 \u0441 \u04222\u0414 \u0438 \u0441\u044a\u043e\u0431\u0449\u0430\u0432\u0430, \u0447\u0435 \u043f\u0435\u043f\u0442\u0438\u0434\u044a\u0442 \u0432\u043e\u0434\u0438 \u0434\u043e \u043d\u0430\u043c\u0430\u043b\u044f\u0432\u0430\u043d\u0435 \u043d\u0430 \u0442\u0435\u0433\u043b\u043e\u0442\u043e \u043d\u0430 \u0442\u0435\u0437\u0438 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0438 \u0441 \u043e\u043a\u043e\u043b\u043e 6 % (6.4 \u043a\u0433 \u0441\u0440\u0435\u0434\u043d\u043e) [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26284720\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">17<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].<\/span><\/span><\/span><\/span><\/span><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0412 \u0442\u0440\u0435\u0442\u0438\u044f \u0441\u043b\u0443\u0447\u0430\u0439 \u0435 \u0438\u0437\u0441\u043b\u0435\u0434\u0432\u0430\u043d \u0435\u0444\u0435\u043a\u0442\u044a\u0442 \u043d\u0430 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0432\u044a\u0440\u0445\u0443 \u0434\u044a\u043b\u0433\u043e\u0441\u0440\u043e\u0447\u043d\u043e\u0442\u043e \u043f\u043e\u0434\u0434\u044a\u0440\u0436\u0430\u043d\u0435 \u043d\u0430 \u0437\u0430\u0433\u0443\u0431\u0430 \u043d\u0430 \u0442\u0435\u0433\u043b\u043e \u043f\u0440\u0438 \u043b\u0438\u0446\u0430 \u0441\u044a\u0441 \u0437\u0430\u0442\u043b\u044a\u0441\u0442\u044f\u0432\u0430\u043d\u0435 \u0438 \u0441\u044a\u0449\u043e \u0441\u0430 \u043e\u0442\u0447\u0435\u0442\u0435\u043d\u0438 \u0431\u043b\u0430\u0433\u043e\u043f\u0440\u0438\u044f\u0442\u043d\u0438 \u0440\u0435\u0437\u0443\u043b\u0442\u0430\u0442\u0438 [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23812094\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">18<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].<\/span><\/li><\/ul><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0435 \u043e\u0434\u043e\u0431\u0440\u0435\u043d \u043e\u0442 \u0415\u041c\u0410 \u0437\u0430 \u0443\u043f\u043e\u0442\u0440\u0435\u0431\u0430 \u0438 \u043f\u0440\u0438 \u044e\u043d\u043e\u0448\u0438 \u0441\u044a\u0441 \u0437\u0430\u0442\u043b\u044a\u0441\u0442\u044f\u0432\u0430\u043d\u0435 \u043d\u0430 \u0432\u044a\u0437\u0440\u0430\u0441\u0442 12-17 \u0433\u043e\u0434\u0438\u043d\u0438 \u0432\u044a\u0437 \u043e\u0441\u043d\u043e\u0432\u0430 \u043d\u0430 \u043f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0435 \u043d\u0430 \u043f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0435 \u0441 251 \u043b\u0438\u0446\u0430. \u0418\u0437\u043f\u0438\u0442\u0432\u0430\u043d\u0435\u0442\u043e \u0432\u043a\u043b\u044e\u0447\u0432\u0430 125 \u044e\u043d\u043e\u0448\u0438 \u0432 \u0433\u0440\u0443\u043f\u0430\u0442\u0430 \u0441 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0438 126 \u044e\u043d\u043e\u0448\u0438 \u0432 \u0433\u0440\u0443\u043f\u0430\u0442\u0430 \u0441 \u043f\u043b\u0430\u0446\u0435\u0431\u043e.<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0413\u0440\u0443\u043f\u0430\u0442\u0430 \u0441 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u043f\u043e\u043a\u0430\u0437\u0432\u0430 \u0437\u043d\u0430\u0447\u0438\u0442\u0435\u043b\u043d\u043e \u043f\u043e\u0434\u043e\u0431\u0440\u0435\u043d\u0438\u0435 \u043d\u0430 \u0418\u0422\u041c-\u0437\u0430-\u0432\u044a\u0437\u0440\u0430\u0441\u0442 (Z-score) \u0432 \u0441\u0440\u0430\u0432\u043d\u0435\u043d\u0438\u0435 \u0441 \u0433\u0440\u0443\u043f\u0430\u0442\u0430 \u043d\u0430 \u043f\u043b\u0430\u0446\u0435\u0431\u043e \u0441\u043b\u0435\u0434 56 \u0441\u0435\u0434\u043c\u0438\u0446\u0438. \u041e\u0441\u0432\u0435\u043d \u0442\u043e\u0432\u0430 \u043f\u043e-\u0433\u043e\u043b\u044f\u043c \u0431\u0440\u043e\u0439 \u0443\u0447\u0430\u0441\u0442\u043d\u0438\u0446\u0438 \u0432 \u0433\u0440\u0443\u043f\u0430\u0442\u0430 \u043d\u0430 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0441\u0430 \u043f\u043e\u0441\u0442\u0438\u0433\u043d\u0430\u043b\u0438 \u043d\u0430\u043c\u0430\u043b\u0435\u043d\u0438\u0435 \u043d\u0430 \u0418\u0422\u041c \u0441 \u043f\u043e\u043d\u0435 5% \u0438 10% \u0432 \u0441\u0440\u0430\u0432\u043d\u0435\u043d\u0438\u0435 \u0441 \u0433\u0440\u0443\u043f\u0430\u0442\u0430 \u043d\u0430 \u043f\u043b\u0430\u0446\u0435\u0431\u043e [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa1916038\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">19<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].<\/span><\/p><h3 dir=\"ltr\" style=\"line-height: 1.38; margin-top: 16pt; margin-bottom: 4pt;\"><span style=\"font-size: 13.999999999999998pt; font-family: Arial,sans-serif; color: #434343; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u043f\u043e\u0434\u043e\u0431\u0440\u044f\u0432\u0430 \u043a\u043e\u043d\u0442\u0440\u043e\u043b\u0430 \u043d\u0430 \u043a\u0440\u044a\u0432\u043d\u0430\u0442\u0430 \u0437\u0430\u0445\u0430\u0440 \u043f\u0440\u0438 \u0442\u0438\u043f 2 \u0434\u0438\u0430\u0431\u0435\u0442\u00a0<\/span><\/h3><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0414\u0440\u0443\u0433\u0430 \u043e\u0441\u043d\u043e\u0432\u043d\u0430 \u0438 \u043e\u0434\u043e\u0431\u0440\u0435\u043d\u0430 \u0443\u043f\u043e\u0442\u0440\u0435\u0431\u0430 \u043d\u0430 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0435 \u0437\u0430 \u043a\u043e\u043d\u0442\u0440\u043e\u043b \u043d\u0430 \u043a\u0440\u044a\u0432\u043d\u0430 \u0437\u0430\u0445\u0430\u0440 \u043f\u0440\u0438 \u04222\u0414. \u0422\u043e \u0441\u0435 \u043e\u0441\u043d\u043e\u0432\u0430\u0432\u0430 \u043d\u0430 \u0448\u0435\u0441\u0442 \u043f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0438\u044f (\u0444\u0430\u0437\u0430 3), \u0438\u0437\u0432\u0435\u0441\u0442\u043d\u0438 \u043a\u0430\u0442\u043e \u043f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0438\u044f\u0442\u0430 LEAD.<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0422\u0435 \u0441\u0440\u0430\u0432\u043d\u044f\u0432\u0430\u0442 \u0433\u043b\u044e\u043a\u043e\u0437\u043e-\u043f\u043e\u043d\u0438\u0436\u0430\u0432\u0430\u0449\u0438\u044f \u0435\u0444\u0435\u043a\u0442 \u043d\u0430 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0441 \u043f\u043b\u0430\u0446\u0435\u0431\u043e, \u043f\u0435\u0440\u043e\u0440\u0430\u043b\u043d\u0438 \u0430\u043d\u0442\u0438\u0434\u0438\u0430\u0431\u0435\u0442\u043d\u0438 \u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u0430, \u0431\u0430\u0437\u0430\u043b\u0435\u043d \u0438\u043d\u0441\u0443\u043b\u0438\u043d \u0438 \u0434\u0440\u0443\u0433\u0438 GLP-1 \u0430\u0433\u043e\u043d\u0438\u0441\u0442\u0438 (\u0435\u043a\u0437\u0435\u043d\u0430\u0442\u0438\u0434).<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0438\u044f\u0442\u0430 \u0441\u0430 \u043f\u0440\u043e\u0434\u044a\u043b\u0436\u0438\u043b\u0438 26-52 \u0441\u0435\u0434\u043c\u0438\u0446\u0438 \u0438 \u0441\u0430 \u0432\u043a\u043b\u044e\u0447\u0432\u0430\u043b\u0438 \u0434\u043d\u0435\u0432\u043d\u0438 \u0434\u043e\u0437\u0438 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0434\u043e 1,8 \u043c\u0433. \u0421\u043f\u043e\u0440\u0435\u0434 \u0434\u0430\u043d\u043d\u0438\u0442\u0435 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0435 \u0434\u043e\u0432\u0435\u043b \u0434\u043e \u043f\u043e-\u0434\u043e\u0431\u044a\u0440 \u0433\u043b\u0438\u043a\u0435\u043c\u0438\u0447\u0435\u043d \u043a\u043e\u043d\u0442\u0440\u043e\u043b \u0438 \u043f\u043e-\u0433\u043e\u043b\u044f\u043c\u043e \u043d\u0430\u043c\u0430\u043b\u044f\u0432\u0430\u043d\u0435 \u043d\u0430 \u0442\u0435\u043b\u0435\u0441\u043d\u043e\u0442\u043e \u0442\u0435\u0433\u043b\u043e \u0441\u0440\u0435\u0434 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0438\u0442\u0435 \u0441 \u04222\u0414 \u0432\u044a\u0432 \u0432\u0441\u0438\u0447\u043a\u0438\u0442\u0435 \u0448\u0435\u0441\u0442 \u0438\u0437\u043f\u0438\u0442\u0432\u0430\u043d\u0438\u044f [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1464-5491.2009.02666.x\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">20<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">, <\/span><a style=\"text-decoration: none;\" href=\"https:\/\/diabetesjournals.org\/care\/article\/32\/1\/84\/28994\/Efficacy-and-Safety-Comparison-of-Liraglutide\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">21<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">, <\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(08)61246-5\/fulltext\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">22<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">, <\/span><a style=\"text-decoration: none;\" href=\"https:\/\/diabetesjournals.org\/care\/article\/32\/7\/1224\/26658\/Efficacy-and-Safety-of-the-Human-Glucagon-Like\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">23<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">, <\/span><a style=\"text-decoration: none;\" href=\"https:\/\/link.springer.com\/article\/10.1007\/s00125-009-1472-y\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">24<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">, <\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(09)60659-0\/fulltext\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">25<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0412\u0441\u0438\u0447\u043a\u0438 \u043f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0438\u044f \u043d\u0430 LEAD \u0441\u0430 \u0432\u043a\u043b\u044e\u0447\u0435\u043d\u0438 \u0432 \u0441\u0438\u0441\u0442\u0435\u043c\u0430\u0442\u0438\u0447\u0435\u043d \u043f\u0440\u0435\u0433\u043b\u0435\u0434 \u043e\u0442 2016 \u0433., \u0432 \u043a\u043e\u0439\u0442\u043e \u0441\u0430 \u043e\u0431\u043e\u0431\u0449\u0435\u043d\u0438 \u0434\u0430\u043d\u043d\u0438 \u043e\u0442 \u043e\u0431\u0449\u043e 43 \u0440\u0430\u043d\u0434\u043e\u043c\u0438\u0437\u0438\u0440\u0430\u043d\u0438 \u043f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0438\u044f \u043d\u0430 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u043f\u0440\u0438 \u04222\u0414. \u0412 \u043f\u0440\u0435\u0433\u043b\u0435\u0434\u0430 \u0441\u0435 \u0441\u044a\u043e\u0431\u0449\u0430\u0432\u0430, \u0447\u0435 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0437\u043d\u0430\u0447\u0438\u0442\u0435\u043b\u043d\u043e \u043d\u0430\u043c\u0430\u043b\u044f\u0432\u0430 \u0433\u043b\u0438\u043a\u0438\u0440\u0430\u043d\u0438\u044f \u0445\u0435\u043c\u043e\u0433\u043b\u043e\u0431\u0438\u043d (HbA1c) \u0441 0,9%-2,2% \u0432 \u0440\u0430\u043c\u043a\u0438\u0442\u0435 \u043d\u0430 6 \u043c\u0435\u0441\u0435\u0446\u0430 \u043e\u0442 \u043d\u0430\u0447\u0430\u043b\u043e\u0442\u043e \u043d\u0430 \u043b\u0435\u0447\u0435\u043d\u0438\u0435\u0442\u043e.<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0418\u0437\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u0442\u0435\u043b\u0438\u0442\u0435 \u0441\u044a\u043e\u0431\u0449\u0430\u0432\u0430\u0442 \u0441\u044a\u0449\u043e, \u0447\u0435 \u0442\u0435\u0440\u0430\u043f\u0438\u044f\u0442\u0430 \u0441 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0435 \u0434\u043e\u0432\u0435\u043b\u0430 \u0434\u043e \u043e\u0442\u0441\u043b\u0430\u0431\u0432\u0430\u043d\u0435 \u0434\u043e -8.65 \u043a\u0433 (\u0441\u043f\u0440\u044f\u043c\u043e \u0438\u0437\u0445\u043e\u0434\u043d\u0430\u0442\u0430 \u0441\u0442\u043e\u0439\u043d\u043e\u0441\u0442) [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27350545\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">26<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].<\/span><\/p><h3 dir=\"ltr\" style=\"line-height: 1.38; margin-top: 16pt; margin-bottom: 4pt;\"><span style=\"font-size: 13.999999999999998pt; font-family: Arial,sans-serif; color: #434343; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u043d\u0430\u043c\u0430\u043b\u044f\u0432\u0430 \u0441\u044a\u0440\u0434\u0435\u0447\u043d\u043e\u0441\u044a\u0434\u043e\u0432\u0438\u044f \u0440\u0438\u0441\u043a \u043f\u0440\u0438 \u0434\u0438\u0430\u0431\u0435\u0442\u0438\u0446\u0438<\/span><\/h3><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u043f\u043e\u043a\u0430\u0437\u0432\u0430 \u0435\u0444\u0438\u043a\u0430\u0441\u043d\u043e\u0441\u0442 \u0437\u0430 \u043d\u0430\u043c\u0430\u043b\u044f\u0432\u0430\u043d\u0435 \u043d\u0430 \u0440\u0438\u0441\u043a\u0430 \u043e\u0442 \u0441\u044a\u0440\u0434\u0435\u0447\u043d\u043e\u0441\u044a\u0434\u043e\u0432\u0438 \u0438\u043d\u0446\u0438\u0434\u0435\u043d\u0442\u0438 \u043f\u0440\u0438 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0438 \u0441 \u04222\u0414.<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041e\u0434\u043e\u0431\u0440\u0435\u043d\u0438\u0435\u0442\u043e \u043c\u0443 \u0437\u0430 \u0442\u043e\u0432\u0430 \u043f\u043e\u043a\u0430\u0437\u0430\u043d\u0438\u0435 \u0441\u0435 \u043e\u0441\u043d\u043e\u0432\u0430\u0432\u0430 \u0434\u043e \u0433\u043e\u043b\u044f\u043c\u0430 \u0441\u0442\u0435\u043f\u0435\u043d \u043d\u0430 \u043f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0435\u0442\u043e LEADER, \u0432 \u043a\u043e\u0435\u0442\u043e \u0443\u0447\u0430\u0441\u0442\u0432\u0430\u0442 \u043d\u0430\u0434 9000 \u0443\u0447\u0430\u0441\u0442\u043d\u0438\u0446\u0438 \u0438 \u0447\u0438\u0439\u0442\u043e \u0441\u0440\u0435\u0434\u0435\u043d \u043f\u0435\u0440\u0438\u043e\u0434 \u043d\u0430 \u043f\u0440\u043e\u0441\u043b\u0435\u0434\u044f\u0432\u0430\u043d\u0435 \u0435 3,8 \u0433\u043e\u0434\u0438\u043d\u0438 [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27295427\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">27<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0412 \u043f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0435\u0442\u043e LEADER \u0435\u0434\u043d\u043e\u043a\u0440\u0430\u0442\u043d\u0430\u0442\u0430 \u0434\u043d\u0435\u0432\u043d\u0430 \u0434\u043e\u0437\u0430 \u043e\u0442 1,8 \u043c\u0433 \u043b\u0438\u0440\u0430\u0433\u043b\u0443\u0442\u0438\u0434 \u0434\u0435\u043c\u043e\u043d\u0441\u0442\u0440\u0438\u0440\u0430 \u0437\u043d\u0430\u0447\u0438\u0442\u0435\u043b\u043d\u0430 \u0435\u0444\u0435\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442 \u0437\u0430 \u043d\u0430\u043c\u0430\u043b\u044f\u0432\u0430\u043d\u0435 \u043d\u0430 \u043f\u043e\u044f\u0432\u0430\u0442\u0430 \u043d\u0430 \u0433\u043e\u043b\u0435\u043c\u0438 \u043d\u0435\u0436\u0435\u043b\u0430\u043d\u0438 \u0441\u044a\u0440\u0434\u0435\u0447\u043d\u043e\u0441\u044a\u0434\u043e\u0432\u0438 \u0438\u043d\u0446\u0438\u0434\u0435\u043d\u0442\u0438, \u043a\u0430\u0442\u043e \u0438\u043d\u0444\u0430\u0440\u043a\u0442\u0438 \u0438 \u0438\u043d\u0441\u0443\u043b\u0442\u0438.<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0435\u0442\u043e \u043f\u043e\u043a\u0430\u0437\u0432\u0430, \u0447\u0435 \u0440\u0438\u0441\u043a\u044a\u0442 \u043e\u0442 \u0444\u0430\u0442\u0430\u043b\u0435\u043d \u0438\u043d\u0444\u0430\u0440\u043a\u0442 \u043d\u0430 \u043c\u0438\u043e\u043a\u0430\u0440\u0434\u0430 (\u0441\u044a\u0440\u0434\u0435\u0447\u0435\u043d \u0443\u0434\u0430\u0440) \u0435 \u0441 40% \u043f\u043e-\u043d\u0438\u0441\u044a\u043a, \u0430 \u0440\u0438\u0441\u043a\u044a\u0442 \u043e\u0442 \u0444\u0430\u0442\u0430\u043b\u0435\u043d \u0438\u043d\u0441\u0443\u043b\u0442 \u0435 \u0441 36% \u043f\u043e-\u043d\u0438\u0441\u044a\u043a \u0441\u0440\u0435\u0434 \u0443\u0447\u0430\u0441\u0442\u043d\u0438\u0446\u0438\u0442\u0435. \u041e\u0441\u0432\u0435\u043d \u0442\u043e\u0432\u0430 \u043e\u0431\u0449\u0438\u044f\u0442 \u0440\u0438\u0441\u043a \u043e\u0442 \u0441\u044a\u0440\u0434\u0435\u0447\u043d\u043e\u0441\u044a\u0434\u043e\u0432\u0438 \u0438\u043d\u0446\u0438\u0434\u0435\u043d\u0442\u0438 \u0435 \u0441\u043f\u0430\u0434\u043d\u0430\u043b \u0441 13%, \u0430 \u0440\u0438\u0441\u043a\u044a\u0442 \u043e\u0442 \u0441\u043c\u044a\u0440\u0442 \u043f\u043e \u043a\u0430\u043a\u0432\u0430\u0442\u043e \u0438 \u0434\u0430 \u0435 \u043f\u0440\u0438\u0447\u0438\u043d\u0430 \u0435 \u043d\u0430\u043c\u0430\u043b\u044f\u043b \u0441 15% \u0432 \u0441\u0440\u0430\u0432\u043d\u0435\u043d\u0438\u0435 \u0441 \u043f\u043b\u0430\u0446\u0435\u0431\u043e \u0433\u0440\u0443\u043f\u0430\u0442\u0430 [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5118235\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">28<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].<\/span><\/p><h3 dir=\"ltr\" style=\"line-height: 1.3800000000000001; margin-top: 12pt; margin-bottom: 12pt;\"><span style=\"font-size: 13.999999999999998pt; font-family: Arial,sans-serif; color: #434343; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0438 \u0431\u043e\u043b\u0435\u0441\u0442\u0442\u0430 \u043d\u0430 \u0410\u043b\u0446\u0445\u0430\u0439\u043c\u0435\u0440<\/span><\/h3><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041f\u0440\u0435\u0434\u0432\u0430\u0440\u0438\u0442\u0435\u043b\u043d\u0438 \u0434\u0430\u043d\u043d\u0438 \u0441\u043e\u0447\u0430\u0442, \u0447\u0435 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u043c\u043e\u0436\u0435 \u0434\u0430 \u043e\u043a\u0430\u0436\u0435 \u043f\u0440\u043e\u0442\u0438\u0432\u043e\u0432\u044a\u0437\u043f\u0430\u043b\u0438\u0442\u0435\u043b\u043d\u043e \u0438 \u043d\u0435\u0432\u0440\u043e\u043f\u0440\u043e\u0442\u0435\u043a\u0442\u0438\u0432\u043d\u043e \u0434\u0435\u0439\u0441\u0442\u0432\u0438\u0435 \u043f\u0440\u0438 \u0440\u0430\u0437\u043b\u0438\u0447\u043d\u0438 \u0434\u0435\u0433\u0435\u043d\u0435\u0440\u0430\u0442\u0438\u0432\u043d\u0438 \u0437\u0430\u0431\u043e\u043b\u044f\u0432\u0430\u043d\u0438\u044f, \u043a\u0430\u0442\u043e \u043d\u0430\u043f\u0440\u0438\u043c\u0435\u0440 \u0431\u043e\u043b\u0435\u0441\u0442\u0442\u0430 \u043d\u0430 \u0410\u043b\u0446\u0445\u0430\u0439\u043c\u0435\u0440. \u041d\u0430\u043f\u0440\u0438\u043c\u0435\u0440, \u043f\u0440\u043e\u0432\u0435\u0434\u0435\u043d\u043e \u0435 \u043a\u043b\u0438\u043d\u0438\u0447\u043d\u043e \u043f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0435 \u0437\u0430 \u043e\u0446\u0435\u043d\u043a\u0430 \u043d\u0430 \u0435\u0444\u0435\u043a\u0442\u0430 \u043d\u0430 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0432\u044a\u0440\u0445\u0443 \u0440\u0430\u0437\u043b\u0438\u0447\u043d\u0438 \u0430\u0441\u043f\u0435\u043a\u0442\u0438 \u043d\u0430 \u0431\u043e\u043b\u0435\u0441\u0442\u0442\u0430 \u043d\u0430 \u0410\u043b\u0446\u0445\u0430\u0439\u043c\u0435\u0440 [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/alz-journals.onlinelibrary.wiley.com\/doi\/abs\/10.1002\/alz.057848\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">29<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].\u00a0<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041f\u043e-\u043a\u043e\u043d\u043a\u0440\u0435\u0442\u043d\u043e, \u043f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0435\u0442\u043e \u0438\u0437\u0441\u043b\u0435\u0434\u0432\u0430 \u0443\u0441\u0432\u043e\u044f\u0432\u0430\u043d\u0435\u0442\u043e \u043d\u0430 \u0433\u043b\u044e\u043a\u043e\u0437\u0430 \u0432 \u043c\u043e\u0437\u044a\u043a\u0430, \u043a\u043e\u0433\u043d\u0438\u0442\u0438\u0432\u043d\u0438\u0442\u0435 \u043f\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u0438, \u043e\u0431\u0435\u043c\u0430 \u043d\u0430 \u043a\u043e\u0440\u0430\u0442\u0430 \u0438 \u0431\u0435\u0437\u043e\u043f\u0430\u0441\u043d\u043e\u0441\u0442\u0442\u0430 \u043f\u0440\u0438 \u043b\u0438\u0446\u0430 \u0441 \u043b\u0435\u043a\u0430 \u0434\u043e \u0443\u043c\u0435\u0440\u0435\u043d\u0430 \u0444\u043e\u0440\u043c\u0430 \u043d\u0430 \u0431\u043e\u043b\u0435\u0441\u0442\u0442\u0430 \u043d\u0430 \u0410\u043b\u0446\u0445\u0430\u0439\u043c\u0435\u0440.\u00a0<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0435\u0442\u043e \u0432\u043a\u043b\u044e\u0447\u0432\u0430 204 \u0443\u0447\u0430\u0441\u0442\u043d\u0438\u0446\u0438 \u0438 \u0435 \u043f\u0440\u043e\u0432\u0435\u0434\u0435\u043d\u043e \u043a\u0430\u0442\u043e \u0438\u0437\u043f\u0438\u0442\u0432\u0430\u043d\u0435 \u0444\u0430\u0437\u0430 2 \u0437\u0430 \u043f\u0435\u0440\u0438\u043e\u0434 \u043e\u0442 12 \u043c\u0435\u0441\u0435\u0446\u0430. \u041f\u043e \u0432\u0440\u0435\u043c\u0435 \u043d\u0430 \u0442\u043e\u0432\u0430 \u0438\u0437\u043f\u0438\u0442\u0432\u0430\u043d\u0435 \u0443\u0447\u0430\u0441\u0442\u043d\u0438\u0446\u0438\u0442\u0435 \u0441\u0430 \u0431\u0438\u043b\u0438 \u0440\u0430\u0437\u043f\u0440\u0435\u0434\u0435\u043b\u0435\u043d\u0438 \u043d\u0430 \u0441\u043b\u0443\u0447\u0430\u0435\u043d \u043f\u0440\u0438\u043d\u0446\u0438\u043f \u0434\u0430 \u043f\u043e\u043b\u0443\u0447\u0430\u0432\u0430\u0442 \u0438\u043b\u0438 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430, \u0438\u043b\u0438 \u043f\u043b\u0430\u0446\u0435\u0431\u043e.<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0420\u0435\u0437\u0443\u043b\u0442\u0430\u0442\u0438\u0442\u0435 \u043e\u0442 \u043f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0435\u0442\u043e \u043f\u043e\u043a\u0430\u0437\u0432\u0430\u0442 \u0437\u043d\u0430\u0447\u0438\u0442\u0435\u043b\u043d\u043e \u043f\u043e\u0434\u043e\u0431\u0440\u0435\u043d\u0438\u0435 \u043d\u0430 \u043a\u043e\u0433\u043d\u0438\u0442\u0438\u0432\u043d\u0430\u0442\u0430 \u0444\u0443\u043d\u043a\u0446\u0438\u044f \u0438 \u043f\u043e-\u0433\u043e\u043b\u044f\u043c \u043a\u043e\u0440\u0442\u0438\u043a\u0430\u043b\u0435\u043d \u043e\u0431\u0435\u043c \u0432 \u0433\u0440\u0443\u043f\u0430\u0442\u0430, \u043b\u0435\u043a\u0443\u0432\u0430\u043d\u0430 \u0441 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430, \u0432 \u0441\u0440\u0430\u0432\u043d\u0435\u043d\u0438\u0435 \u0441 \u043a\u043e\u043d\u0442\u0440\u043e\u043b\u043d\u0430\u0442\u0430 \u0433\u0440\u0443\u043f\u0430 [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/alz-journals.onlinelibrary.wiley.com\/doi\/abs\/10.1002\/alz.057848\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">29<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">]. \u0412\u0430\u0436\u043d\u043e \u0435 \u043e\u0431\u0430\u0447\u0435 \u0434\u0430 \u0441\u0435 \u043e\u0442\u0431\u0435\u043b\u0435\u0436\u0438, \u0447\u0435 \u0441\u0430 \u043d\u0435\u043e\u0431\u0445\u043e\u0434\u0438\u043c\u0438 \u0434\u043e\u043f\u044a\u043b\u043d\u0438\u0442\u0435\u043b\u043d\u0438 \u0438\u0437\u0441\u043b\u0435\u0434\u0432\u0430\u043d\u0438\u044f, \u0437\u0430 \u0434\u0430 \u0441\u0435 \u043f\u043e\u0442\u0432\u044a\u0440\u0434\u044f\u0442 \u0438 \u0434\u043e\u0440\u0430\u0437\u0432\u0438\u044f\u0442 \u0442\u0435\u0437\u0438 \u0440\u0435\u0437\u0443\u043b\u0442\u0430\u0442\u0438.<\/span><\/p><h2 dir=\"ltr\" style=\"line-height: 1.3800000000000001; margin-top: 12pt; margin-bottom: 12pt;\"><span style=\"font-size: 16pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0437\u0430 \u043e\u0442\u0441\u043b\u0430\u0431\u0432\u0430\u043d\u0435 | \u041a\u0430\u043a\u0432\u043e \u0442\u0440\u044f\u0431\u0432\u0430 \u0434\u0430 \u0437\u043d\u0430\u0435\u0442\u0435?<\/span><\/h2><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0421\u043f\u043e\u0440\u0435\u0434 \u043f\u043e-\u0433\u043e\u043b\u044f\u043c\u0430\u0442\u0430 \u0447\u0430\u0441\u0442 \u043e\u0442 \u043d\u0430\u043b\u0438\u0447\u043d\u0438\u0442\u0435 \u043f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0438\u044f \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u043f\u043e\u0441\u0442\u0438\u0433\u0430 \u0435\u0444\u0435\u043a\u0442 \u043d\u0430 \u043e\u0442\u0441\u043b\u0430\u0431\u0432\u0430\u043d\u0435 \u0447\u0440\u0435\u0437 \u043f\u043e\u0442\u0438\u0441\u043a\u0430\u043d\u0435 \u043d\u0430 \u0430\u043f\u0435\u0442\u0438\u0442\u0430.<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041f\u043e-\u043a\u043e\u043d\u043a\u0440\u0435\u0442\u043d\u043e, \u0438\u0437\u0433\u043b\u0435\u0436\u0434\u0430, \u0447\u0435 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u043d\u0430\u043c\u0430\u043b\u044f\u0432\u0430 \u0433\u043b\u0430\u0434\u0430 \u0447\u0440\u0435\u0437 \u0430\u043a\u0442\u0438\u0432\u0438\u0440\u0430\u043d\u0435 \u043d\u0430 GLP-1 \u0440\u0435\u0446\u0435\u043f\u0442\u043e\u0440\u0438\u0442\u0435 \u0432 \u043e\u0431\u043b\u0430\u0441\u0442\u0438 \u043d\u0430 \u043c\u043e\u0437\u044a\u043a\u0430 \u0441\u0432\u044a\u0440\u0437\u0430\u043d\u0438 \u0441 \u0440\u0435\u0433\u0443\u043b\u0438\u0440\u0430\u043d\u0435\u0442\u043e \u043d\u0430 \u0430\u043f\u0435\u0442\u0438\u0442\u0430, \u043a\u0430\u0442\u043e \u0430\u0440\u043a\u0443\u0430\u0442\u043d\u043e\u0442\u043e \u044f\u0434\u0440\u043e \u0432 \u0445\u0438\u043f\u043e\u0442\u0430\u043b\u0430\u043c\u0443\u0441\u0430 [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8189979\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">30<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].\u00a0<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0422\u0435\u0437\u0438 \u043d\u0435\u0432\u0440\u043e\u043d\u0438 \u0435\u043a\u0441\u043f\u0440\u0435\u0441\u0438\u0440\u0430\u0442 \u0442\u0430\u043a\u0430 \u043d\u0430\u0440\u0435\u0447\u0435\u043d\u0438\u044f \u043f\u0440\u043e\u043e\u043f\u0438\u043e\u043c\u0435\u043b\u0430\u043d\u043e\u043a\u043e\u0440\u0442\u0438\u043d \u0438 \u043a\u043e\u043a\u0430\u0438\u043d- \u0438 \u0430\u043c\u0444\u0435\u0442\u0430\u043c\u0438\u043d-\u0440\u0435\u0433\u0443\u043b\u0438\u0440\u0430\u043d \u0442\u0440\u0430\u043d\u0441\u043a\u0440\u0438\u043f\u0442 (POMC\/CART).<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0434\u0438\u0440\u0435\u043a\u0442\u043d\u043e \u0430\u043a\u0442\u0438\u0432\u0438\u0440\u0430 POMC\/CART \u043d\u0435\u0432\u0440\u043e\u043d\u0438\u0442\u0435, \u043a\u043e\u0435\u0442\u043e \u0432\u043e\u0434\u0438 \u0434\u043e \u043f\u043e\u0432\u0438\u0448\u0435\u043d\u043e \u0443\u0441\u0435\u0449\u0430\u043d\u0435 \u0437\u0430 \u0441\u0438\u0442\u043e\u0441\u0442. \u041f\u0435\u043f\u0442\u0438\u0434\u044a\u0442 \u0441\u044a\u0449\u043e \u0442\u0430\u043a\u0430 \u0438\u043d\u0434\u0438\u0440\u0435\u043a\u0442\u043d\u043e \u043f\u043e\u0442\u0438\u0441\u043a\u0430 \u043d\u044f\u043a\u043e\u043b\u043a\u043e \u0430\u043f\u0435\u0442\u0438\u0442-\u0441\u0442\u0438\u043c\u0443\u043b\u0438\u0440\u0430\u0449\u0438 \u0445\u043e\u0440\u043c\u043e\u043d\u0430, \u043d\u0430\u0440\u0435\u0447\u0435\u043d\u0438 \u043d\u0435\u0432\u0440\u043e\u043f\u0435\u043f\u0442\u0438\u0434 Y (NPY) \u0438 \u0430\u0433\u0443\u0442\u0438-\u0441\u0432\u044a\u0440\u0437\u0430\u043d \u043f\u0435\u043f\u0442\u0438\u0434 (AgRP) [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4215190\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">31<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].\u00a0<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u043c\u043e\u0436\u0435 \u0441\u044a\u0449\u043e \u0442\u0430\u043a\u0430 \u0434\u0430 \u0441\u0442\u0438\u043c\u0443\u043b\u0438\u0440\u0430 \u0441\u0435\u043a\u0440\u0435\u0446\u0438\u044f\u0442\u0430 \u043d\u0430 \u0434\u0440\u0443\u0433 \u043f\u043e\u0442\u0438\u0441\u043a\u0430\u0449 \u0430\u043f\u0435\u0442\u0438\u0442\u0430 \u0445\u043e\u0440\u043c\u043e\u043d, \u043d\u0430\u0440\u0435\u0447\u0435\u043d \u043f\u0435\u043f\u0442\u0438\u0434 YY (PYY), \u043a\u043e\u0439\u0442\u043e \u0441\u044a\u0449\u043e \u0441\u0438\u0433\u043d\u0430\u043b\u0438\u0437\u0438\u0440\u0430 \u043d\u0430 \u043c\u043e\u0437\u044a\u043a\u0430 \u0437\u0430 \u043d\u0430\u043c\u0430\u043b\u044f\u0432\u0430 \u0433\u043b\u0430\u0434\u0430. \u041f\u0435\u043f\u0442\u0438\u0434\u0430 \u043c\u043e\u0436\u0435 \u0434\u0430 \u043f\u0440\u0435\u0432\u0430\u043d\u0442\u0438\u0440\u0430 \u0438 \u0441\u043f\u0430\u0434\u0430 \u043d\u0430 \u0445\u043e\u0440\u043c\u043e\u043d\u0430 \u043d\u0430 \u0441\u0438\u0442\u043e\u0441\u0442\u0442\u0430 &#8211; \u043b\u0435\u043f\u0442\u0438\u043d.<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041b\u0435\u043f\u0442\u0438\u043d\u044a\u0442 \u043e\u0431\u0438\u043a\u043d\u043e\u0432\u0435\u043d\u043e \u0441\u0435 \u043f\u0440\u043e\u0438\u0437\u0432\u0435\u0436\u0434\u0430 \u043e\u0442 \u043c\u0430\u0441\u0442\u043d\u0430\u0442\u0430 \u0442\u044a\u043a\u0430\u043d \u0438 \u043d\u0438\u0432\u0430\u0442\u0430 \u043c\u0443 \u0441\u043f\u0430\u0434\u0430\u0442 \u043f\u043e \u0432\u0440\u0435\u043c\u0435 \u043d\u0430 \u0437\u0430\u0433\u0443\u0431\u0430 \u043d\u0430 \u043c\u0430\u0437\u043d\u0438\u043d\u0438, \u043a\u043e\u0435\u0442\u043e \u0432\u043e\u0434\u0438 \u0434\u043e \u043f\u043e\u0432\u0438\u0448\u0435\u043d \u0433\u043b\u0430\u0434. \u041f\u043e\u0434\u0434\u044a\u0440\u0436\u0430\u043d\u0435\u0442\u043e \u043d\u0430 \u043f\u043e-\u0432\u0438\u0441\u043e\u043a\u0438 \u043d\u0438\u0432\u0430 \u043d\u0430 \u043b\u0435\u043f\u0442\u0438\u043d \u0438 PYY \u043c\u043e\u0436\u0435 \u0441\u044a\u0449\u043e \u0434\u0430 \u043e\u0431\u044f\u0441\u043d\u0438 \u0431\u043b\u0430\u0433\u043e\u043f\u0440\u0438\u044f\u0442\u043d\u0438\u044f \u0435\u0444\u0435\u043a\u0442 \u043d\u0430 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0432\u044a\u0440\u0445\u0443 \u0437\u0430\u0433\u0443\u0431\u0430\u0442\u0430 \u043d\u0430 \u0442\u0435\u0433\u043b\u043e \u0432 \u0434\u044a\u043b\u0433\u043e\u0441\u0440\u043e\u0447\u0435\u043d \u043f\u043b\u0430\u043d [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8189979\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">30<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">, <\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4424381\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">32<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0412 \u0440\u0435\u0437\u0443\u043b\u0442\u0430\u0442 \u043d\u0430 \u0442\u043e\u0432\u0430 \u043d\u044f\u043a\u043e\u043b\u043a\u043e \u0441\u0438\u0441\u0442\u0435\u043c\u0430\u0442\u0438\u0447\u043d\u0438 \u0440\u0435\u0432\u044e\u0442\u0430 \u043f\u043e\u043a\u0430\u0437\u0432\u0430\u0442, \u0447\u0435 \u043f\u043e\u0442\u0438\u0441\u043a\u0430\u0449\u0438\u0442\u0435 \u0430\u043f\u0435\u0442\u0438\u0442\u0430 \u0435\u0444\u0435\u043a\u0442\u0438 \u043d\u0430 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u043c\u043e\u0433\u0430\u0442 \u0434\u0430 \u0434\u043e\u0432\u0435\u0434\u0430\u0442 \u0434\u043e \u0437\u043d\u0430\u0447\u0438\u0442\u0435\u043b\u043d\u0430 \u0437\u0430\u0433\u0443\u0431\u0430 \u043d\u0430 \u0442\u0435\u0433\u043b\u043e.<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041d\u0430\u043f\u0440\u0438\u043c\u0435\u0440 \u0435\u0434\u0438\u043d \u043c\u0435\u0442\u0430-\u0430\u043d\u0430\u043b\u0438\u0437 \u043e\u0442 2022 \u0433. \u0432\u043a\u043b\u044e\u0447\u0432\u0430 \u0441\u0435\u0434\u0435\u043c \u0444\u0430\u0437\u0438 3 \u0438 \u0447\u0435\u0442\u0438\u0440\u0438 \u0440\u0430\u043d\u0434\u043e\u043c\u0438\u0437\u0438\u0440\u0430\u043d\u0438 \u043a\u043e\u043d\u0442\u0440\u043e\u043b\u0438\u0440\u0430\u043d\u0438 \u043f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0438\u044f, \u043a\u043e\u0438\u0442\u043e \u0441\u0430 \u043f\u0440\u043e\u0434\u044a\u043b\u0436\u0438\u043b\u0438 \u043f\u043e\u043d\u0435 \u0435\u0434\u043d\u0430 \u0433\u043e\u0434\u0438\u043d\u0430. \u0410\u043d\u0430\u043b\u0438\u0437\u044a\u0442 \u043e\u0431\u0435\u0434\u0438\u043d\u044f\u0432\u0430 \u0434\u0430\u043d\u043d\u0438 \u043e\u0442 \u043e\u0431\u0449\u043e 6028 \u0432\u044a\u0437\u0440\u0430\u0441\u0442\u043d\u0438 \u0441\u044a\u0441 \u0437\u0430\u0442\u043b\u044a\u0441\u0442\u044f\u0432\u0430\u043d\u0435 \u0438\u043b\u0438 \u043d\u0430\u0434\u043d\u043e\u0440\u043c\u0435\u043d\u043e \u0442\u0435\u0433\u043b\u043e, \u0441\u044a\u0441 \u0438\u043b\u0438 \u0431\u0435\u0437 \u04222\u0414.\u00a0<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0420\u0435\u0437\u0443\u043b\u0442\u0430\u0442\u0438\u0442\u0435 \u0440\u0430\u0437\u043a\u0440\u0438\u0432\u0430\u0442 \u0437\u043d\u0430\u0447\u0438\u0442\u0435\u043b\u043d\u043e \u043d\u0430\u043c\u0430\u043b\u044f\u0432\u0430\u043d\u0435 \u043d\u0430 \u0442\u0435\u0433\u043b\u043e\u0442\u043e \u0441 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430, \u0441\u044a\u0441 \u0441\u0440\u0435\u0434\u043d\u0430 \u0440\u0430\u0437\u043b\u0438\u043a\u0430 \u0432 \u043f\u0440\u043e\u0446\u0435\u043d\u0442\u043d\u043e\u0442\u043e \u0438\u0437\u043c\u0435\u043d\u0435\u043d\u0438\u0435 \u043d\u0430 \u0442\u0435\u0433\u043b\u043e\u0442\u043e \u043e\u0442 -4,81% \u0432 \u0441\u0440\u0430\u0432\u043d\u0435\u043d\u0438\u0435 \u0441 \u043f\u043b\u0430\u0446\u0435\u0431\u043e \u0433\u0440\u0443\u043f\u0430\u0442\u0430 [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/17512433.2022.2130760?needAccess=true\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">33<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].\u00a0<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0414\u0440\u0443\u0433 \u043c\u0435\u0442\u0430-\u0430\u043d\u0430\u043b\u0438\u0437 \u043e\u0442 2022 \u0433. \u0441\u044a\u0449\u043e \u043e\u0431\u0445\u0432\u0430\u0449\u0430 14 \u0440\u0430\u043d\u0434\u043e\u043c\u0438\u0437\u0438\u0440\u0430\u043d\u0438 \u043a\u043e\u043d\u0442\u0440\u043e\u043b\u0438\u0440\u0430\u043d\u0438 \u043f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0438\u044f \u0438 \u0441\u044a\u043e\u0431\u0449\u0430\u0432\u0430, \u0447\u0435 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u043c\u043e\u0436\u0435 \u0434\u0430 \u0434\u043e\u0432\u0435\u0434\u0435 \u0434\u043e \u0437\u043d\u0430\u0447\u0438\u0442\u0435\u043b\u043d\u0430 \u0437\u0430\u0433\u0443\u0431\u0430 \u043d\u0430 \u0442\u0435\u0433\u043b\u043e. \u0414\u0430\u043d\u043d\u0438\u0442\u0435 \u0440\u0430\u0437\u043a\u0440\u0438\u0432\u0430\u0442, \u0447\u0435 3 \u043c\u0433\/\u0434\u0435\u043d \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430, \u043f\u0440\u0438\u0435\u043c\u0430\u043d\u0438 \u0432 \u043f\u0440\u043e\u0434\u044a\u043b\u0436\u0435\u043d\u0438\u0435 \u043d\u0430 20-56 \u0441\u0435\u0434\u043c\u0438\u0446\u0438, \u0432\u043e\u0434\u044f\u0442 \u0434\u043e \u0441\u0440\u0435\u0434\u043d\u043e \u043e\u043a\u043e\u043b\u043e 4,9 \u043a\u0433 \u043f\u043e-\u0433\u043e\u043b\u044f\u043c\u0430 \u0437\u0430\u0433\u0443\u0431\u0430 \u043d\u0430 \u0442\u0435\u0433\u043b\u043e \u0432 \u0441\u0440\u0430\u0432\u043d\u0435\u043d\u0438\u0435 \u0441 \u043f\u043b\u0430\u0446\u0435\u0431\u043e [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9325632\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">34<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].<\/span><\/p><h2 dir=\"ltr\" style=\"line-height: 1.3800000000000001; margin-top: 12pt; margin-bottom: 12pt;\"><span style=\"font-size: 16pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0438\u043b\u0438 \u041e\u0437\u0435\u043c\u043f\u0438\u043a \u0437\u0430 \u043e\u0442\u0441\u043b\u0430\u0431\u0432\u0430\u043d\u0435?<\/span><\/h2><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041f\u043e\u0434\u043e\u0431\u043d\u043e \u043d\u0430 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430, <a href=\"https:\/\/drmarinov.com\/otslabvane-s-ozempic\/\">\u041e\u0437\u0435\u043c\u043f\u0438\u043a (\u0441\u0435\u043c\u0430\u0433\u043b\u0443\u0442\u0438\u0434, \u0412\u0435\u0433\u043e\u0432\u0438)<\/a> \u0435 \u0438\u043d\u043a\u0440\u0435\u0442\u0438\u043d\u043e\u0432 \u043c\u0438\u043c\u0435\u0442\u0438\u043a, \u043a\u043e\u0438\u0442\u043e \u0430\u043a\u0442\u0438\u0432\u0438\u0440\u0430 GLP-1 \u0440\u0435\u0446\u0435\u043f\u0442\u043e\u0440\u0438\u0442\u0435 \u0438 \u043f\u043e\u043d\u0430\u0441\u0442\u043e\u044f\u0449\u0435\u043c \u0435 \u043e\u0434\u043e\u0431\u0440\u0435\u043d \u043e\u0442 \u0415\u041c\u0410 \u0437\u0430 \u0433\u043b\u0438\u043a\u0435\u043c\u0438\u0447\u0435\u043d \u043a\u043e\u043d\u0442\u0440\u043e\u043b \u043f\u0440\u0438 \u04222\u0414 \u0438 \u043e\u0442\u0441\u043b\u0430\u0431\u0432\u0430\u043d\u0435.<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0415\u0434\u043d\u0430 \u043e\u0442 \u043e\u0441\u043d\u043e\u0432\u043d\u0438\u0442\u0435 \u0440\u0430\u0437\u043b\u0438\u043a\u0438 \u0441 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0435, \u0447\u0435 \u041e\u0437\u0435\u043c\u043f\u0438\u043a, \u0438\u043c\u0430 \u043c\u043d\u043e\u0433\u043e \u043f\u043e-\u0434\u044a\u043b\u044a\u0433 \u043f\u043e\u043b\u0443\u0436\u0438\u0432\u043e\u0442, \u043a\u043e\u0435\u0442\u043e \u043f\u043e\u0437\u0432\u043e\u043b\u044f\u0432\u0430 \u043f\u0440\u0438\u043b\u0430\u0433\u0430\u043d\u0435\u0442\u043e \u043c\u0443 \u0432\u0435\u0434\u043d\u044a\u0436 \u0441\u0435\u0434\u043c\u0438\u0447\u043d\u043e, \u0430 \u043d\u0435 \u0432\u0435\u0434\u043d\u044a\u0436 \u0434\u043d\u0435\u0432\u043d\u043e [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8736331\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">35<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">]. \u041e\u0437\u0435\u043c\u043f\u0438\u043a \u0435 \u043e\u0434\u043e\u0431\u0440\u0435\u043d \u0438 \u0437\u0430 \u043d\u0430\u043c\u0430\u043b\u044f\u0432\u0430\u043d\u0435 \u043d\u0430 \u0441\u044a\u0440\u0434\u0435\u0447\u043d\u043e\u0441\u044a\u0434\u043e\u0432\u0438\u044f \u0440\u0438\u0441\u043a \u043f\u0440\u0438 \u04222\u0414 [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8717485\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">36<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0415\u0434\u0438\u043d \u043c\u0435\u0442\u0430-\u0430\u043d\u0430\u043b\u0438\u0437\u00a0 \u0441\u0440\u0430\u0432\u043d\u044f\u0432\u0430 \u0435\u0444\u0435\u043a\u0442\u0438\u0442\u0435 \u043e\u0442 \u043d\u0430\u043c\u0430\u043b\u044f\u0432\u0430\u043d\u0435\u0442\u043e \u043d\u0430 \u0442\u0435\u0433\u043b\u043e\u0442\u043e \u043d\u0430 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0438 \u041e\u0437\u0435\u043c\u043f\u0438\u043a. \u0410\u043d\u0430\u043b\u0438\u0437\u044a\u0442 \u0432\u043a\u043b\u044e\u0447\u0432\u0430 23 \u0440\u0430\u043d\u0434\u043e\u043c\u0438\u0437\u0438\u0440\u0430\u043d\u0438 \u043a\u043e\u043d\u0442\u0440\u043e\u043b\u0438\u0440\u0430\u043d\u0438 \u043f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0438\u044f \u0441 \u043e\u0431\u0449\u043e 11 545 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0438 \u0438 \u0447\u0435\u0442\u0438\u0440\u0438 \u0438\u043d\u0442\u0435\u0440\u0432\u0435\u043d\u0446\u0438\u0438 (\u041e\u0437\u0435\u043c\u043f\u0438\u043a 2,4 \u043c\u0433, \u041e\u0437\u0435\u043c\u043f\u0438\u043a 1,0 \u043c\u0433, \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 3,0 \u043c\u0433 \u0438 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 1,8 \u043c\u0433).<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0420\u0435\u0437\u0443\u043b\u0442\u0430\u0442\u0438\u0442\u0435 \u043f\u043e\u043a\u0430\u0437\u0432\u0430\u0442, \u0447\u0435 \u043f\u043e \u043e\u0442\u043d\u043e\u0448\u0435\u043d\u0438\u0435 \u043d\u0430 \u0435\u0444\u0438\u043a\u0430\u0441\u043d\u043e\u0441\u0442\u0442\u0430 \u043d\u0430 \u0437\u0430\u0433\u0443\u0431\u0430\u0442\u0430 \u043d\u0430 \u0442\u0435\u0433\u043b\u043e \u043d\u0430\u0439-\u0434\u043e\u0431\u0440\u0438 \u0440\u0435\u0437\u0443\u043b\u0442\u0430\u0442\u0438 \u0438\u043c\u0430 \u041e\u0437\u0435\u043c\u043f\u0438\u043a 2,4 \u043c\u0433 (\u221212.47 \u043a\u0433), \u0441\u043b\u0435\u0434\u0432\u0430\u043d \u043e\u0442 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 3,0 \u043c\u0433 (\u22125.24 \u043a\u0433), \u041e\u0437\u0435\u043c\u043f\u0438\u043a 1,0 \u043c\u0433 (\u22123.74 \u043a\u0433) \u0438 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 1,8 \u043c\u0433 (\u22123.74 \u043a\u0433). \u041e\u0437\u0435\u043c\u043f\u0438\u043a 2,4\u043c\u0433 \u0438 \u041e\u0437\u0435\u043c\u043f\u0438\u043a 1,0\u043c\u0433, \u043a\u0430\u043a\u0442\u043e \u0438 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 1,8\u043c\u0433, \u0441\u0430 \u0431\u0438\u043b\u0438 \u043f\u043e-\u0435\u0444\u0435\u043a\u0442\u0438\u0432\u043d\u0438 \u0437\u0430 \u043d\u0430\u043c\u0430\u043b\u044f\u0432\u0430\u043d\u0435 \u043d\u0430 \u043d\u0438\u0432\u0430\u0442\u0430 \u043d\u0430 HbA1c \u0432 \u0441\u0440\u0430\u0432\u043d\u0435\u043d\u0438\u0435 \u0441 \u043f\u043b\u0430\u0446\u0435\u0431\u043e.<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0429\u043e \u0441\u0435 \u043e\u0442\u043d\u0430\u0441\u044f \u0434\u043e \u0431\u0435\u0437\u043e\u043f\u0430\u0441\u043d\u043e\u0441\u0442\u0442\u0430, \u043d\u0430\u0439-\u0432\u0438\u0441\u043e\u043a\u0430 \u0435 \u0447\u0435\u0441\u0442\u043e\u0442\u0430\u0442\u0430 \u043d\u0430 \u043d\u0435\u0436\u0435\u043b\u0430\u043d\u0438\u0442\u0435 \u0441\u044a\u0431\u0438\u0442\u0438\u044f \u043f\u0440\u0438 \u041e\u0437\u0435\u043c\u043f\u0438\u043a 2,4 \u043c\u0433, \u0441\u043b\u0435\u0434\u0432\u0430\u043d \u043e\u0442 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 3,0 \u043c\u0433, \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 1,8 \u043c\u0433 \u0438 \u041e\u0437\u0435\u043c\u043f\u0438\u043a 1,0 \u043c\u0433. \u0427\u0435\u0441\u0442\u043e\u0442\u0430\u0442\u0430 \u043d\u0430 \u0441\u0435\u0440\u0438\u043e\u0437\u043d\u0438\u0442\u0435 \u043d\u0435\u0436\u0435\u043b\u0430\u043d\u0438 \u0441\u044a\u0431\u0438\u0442\u0438\u044f \u0435 \u043d\u0430\u0439-\u0432\u0438\u0441\u043e\u043a\u0430 \u043f\u0440\u0438 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 3,0 \u043c\u0433, \u0441\u043b\u0435\u0434\u0432\u0430\u043d \u043e\u0442 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 1,8\u043c\u0433, \u041e\u0437\u0435\u043c\u043f\u0438\u043a 2,4\u043c\u0433 \u0438 \u041e\u0437\u0435\u043c\u043f\u0438\u043a 1,0\u043c\u0433. \u0425\u0438\u043f\u043e\u0433\u043b\u0438\u043a\u0435\u043c\u0438\u0447\u043d\u0438\u0442\u0435 \u0441\u044a\u0431\u0438\u0442\u0438\u044f \u0441\u0430 \u0431\u0438\u043b\u0438 \u043d\u0430\u0439-\u0447\u0435\u0441\u0442\u0438 \u043f\u0440\u0438 \u041e\u0437\u0435\u043c\u043f\u0438\u043a 2,4 \u043c\u0433, \u0441\u043b\u0435\u0434\u0432\u0430\u043d \u043e\u0442 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 3,0 \u043c\u0433, \u041e\u0437\u0435\u043c\u043f\u0438\u043a 1,0 \u043c\u0433 \u0438 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 1,8 \u043c\u0433 [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9738168\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">37<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].<\/span><\/p><p dir=\"ltr\"><img decoding=\"async\" class=\"alignnone size-full wp-image-5139\" src=\"https:\/\/drmarinov.com\/wp-content\/uploads\/2024\/02\/ozempic-vs-saxenda.png\" alt=\"ozempic-vs-saxenda\" width=\"550\" height=\"215\" srcset=\"https:\/\/drmarinov.com\/wp-content\/uploads\/2024\/02\/ozempic-vs-saxenda.png 550w, https:\/\/drmarinov.com\/wp-content\/uploads\/2024\/02\/ozempic-vs-saxenda-300x117.png 300w, https:\/\/drmarinov.com\/wp-content\/uploads\/2024\/02\/ozempic-vs-saxenda-18x7.png 18w\" sizes=\"(max-width: 550px) 100vw, 550px\" \/><\/p><h2 dir=\"ltr\" style=\"line-height: 1.3800000000000001; margin-top: 12pt; margin-bottom: 12pt;\"><span style=\"font-size: 16pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0438\u043b\u0438 \u041c\u0443\u043d\u0434\u0436\u0430\u0440\u043e \u0437\u0430 \u043e\u0442\u0441\u043b\u0430\u0431\u0432\u0430\u043d\u0435?<\/span><\/h2><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041c\u0443\u043d\u0434\u0436\u0430\u0440\u043e (\u0442\u0438\u0440\u0437\u0435\u043f\u0430\u0442\u0438\u0434, \u0417\u0435\u043f\u0431\u0430\u0443\u043d\u0434) \u0435 \u0434\u0432\u043e\u0435\u043d \u0438\u043d\u043a\u0440\u0435\u0442\u0438\u043d\u043e\u0432 \u0430\u0433\u043e\u043d\u0438\u0441\u0442, \u0442\u044a\u0439 \u043a\u0430\u0442\u043e \u0438\u043c\u0438\u0442\u0438\u0440\u0430 \u0444\u0443\u043d\u043a\u0446\u0438\u044f\u0442\u0430 \u0438 \u043d\u0430 \u0434\u0440\u0443\u0433 \u0438\u043d\u043a\u0440\u0435\u0442\u0438\u043d\u043e\u0432 \u0445\u043e\u0440\u043c\u043e\u043d &#8211; \u0433\u043b\u044e\u043a\u043e\u0437\u043e\u0437\u0430\u0432\u0438\u0441\u0438\u043c\u0438\u044f \u0438\u043d\u0441\u0443\u043b\u0438\u043d\u043e\u0442\u0440\u043e\u043f\u0435\u043d \u043f\u043e\u043b\u0438\u043f\u0435\u043f\u0442\u0438\u0434 (GIP) [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8881610\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">38<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">]. \u041c\u0443\u043d\u0434\u0436\u0430\u0440\u043e \u0435 \u043f\u044a\u0440\u0432\u043e \u0432 \u043a\u043b\u0430\u0441\u0430 \u0441\u0438 \u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u043e, \u043a\u043e\u0435\u0442\u043e \u0435\u0434\u0432\u0430 \u043d\u0430\u0441\u043a\u043e\u0440\u043e (2023 \u0433.) \u0431\u0435\u0448\u0435 \u043e\u0434\u043e\u0431\u0440\u0435\u043d\u043e \u0437\u0430 \u043e\u0442\u0441\u043b\u0430\u0431\u0432\u0430\u043d\u0435 [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9268041\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">39<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].\u00a0<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0422\u043e\u0439 \u0441\u044a\u0449\u043e \u0441\u0435 \u043f\u0440\u0438\u043b\u0430\u0433\u0430 \u0432\u0435\u0434\u043d\u044a\u0436 \u0441\u0435\u0434\u043c\u0438\u0447\u043d\u043e. \u041c\u0443\u043d\u0434\u0436\u0430\u0440\u043e \u043f\u043e\u043a\u0430\u0437\u0432\u0430 \u043f\u043e-\u0434\u043e\u0431\u0440\u0438 \u0440\u0435\u0437\u0443\u043b\u0442\u0430\u0442\u0438 \u043f\u043e \u043e\u0442\u043d\u043e\u0448\u0435\u043d\u0438\u0435 \u043d\u0430 \u0437\u0430\u0433\u0443\u0431\u0430\u0442\u0430 \u043d\u0430 \u0442\u0435\u0433\u043b\u043e \u0432 \u0441\u0440\u0430\u0432\u043d\u0435\u043d\u0438\u0435 \u043a\u0430\u043a\u0442\u043e \u0441\u044a\u0441 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430, \u0442\u0430\u043a\u0430 \u0438 \u0441 \u041e\u0437\u0435\u043c\u043f\u0438\u043a, \u043d\u0435\u0437\u0430\u0432\u0438\u0441\u0438\u043c\u043e \u043e\u0442 \u0434\u043e\u0437\u0430\u0442\u0430 <\/span><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">[<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2107519\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">40<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].\u00a0<\/span><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"><br \/><\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041f\u0440\u0435\u0437 2024, \u041c\u0443\u043d\u0434\u0436\u0430\u0440\u043e \u0431\u0435 \u0443\u0434\u043e\u0431\u0440\u0435\u043d \u0437\u0430 \u0443\u043f\u043e\u0442\u0440\u0435\u0431\u0430 \u0432 \u0415\u0432\u0440\u043e\u043f\u0430 \u0441 \u0446\u0435\u043b \u043e\u0442\u0441\u043b\u0430\u0431\u0432\u0430\u043d\u0435 \u0438 \u043a\u043e\u043d\u0442\u0440\u043e\u043b \u043d\u0430 \u0442\u0438\u043f 2 \u0434\u0438\u0430\u0431\u0435\u0442. \u0410 \u043f\u0440\u0435\u0437 2025-\u0442\u0430 \u041c\u0443\u043d\u0434\u0436\u0430\u0440\u043e \u0435 \u0432\u0435\u0447\u0435 \u043d\u0430\u043b\u0438\u0447\u0435\u043d \u0438 \u0432 \u0431\u044a\u043b\u0433\u0430\u0440\u0438\u044f. <a href=\"https:\/\/drmarinov.com\/otslabvane-s-mounjaro\/\">\u0412\u0441\u0438\u0447\u043a\u043e \u0437\u0430 \u041c\u0443\u043d\u0434\u0436\u0430\u0440\u043e \u0437\u0430 \u043e\u0442\u0441\u043b\u0430\u0431\u0432\u0430\u043d\u0435 \u043c\u043e\u0436\u0435 \u0434\u0430 <span style=\"text-decoration: underline;\">\u043f\u0440\u043e\u0447\u0435\u0442\u0435\u0442\u0435 \u0442\u0443\u043a<\/span><\/a>.<\/span><\/p><h2 dir=\"ltr\" style=\"line-height: 1.38; margin-top: 18pt; margin-bottom: 6pt;\"><span style=\"font-size: 16pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0421\u0442\u0440\u0430\u043d\u0438\u0447\u043d\u0438 \u0435\u0444\u0435\u043a\u0442\u0438 \u043d\u0430 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430<\/span><\/h2><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0418\u0437\u0441\u043b\u0435\u0434\u0432\u0430\u043d\u0438\u044f\u0442\u0430 \u0440\u0430\u0437\u043a\u0440\u0438\u0432\u0430\u0442, \u0447\u0435 \u043f\u0435\u043f\u0442\u0438\u0434\u044a\u0442 \u0441\u0435 \u043f\u043e\u043d\u0430\u0441\u044f \u0434\u043e\u0431\u0440\u0435 \u043e\u0442 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0438 \u0441\u044a\u0441 \u0437\u0430\u0442\u043b\u044a\u0441\u0442\u044f\u0432\u0430\u043d\u0435 \u0438 \u0434\u0438\u0430\u0431\u0435\u0442, \u0430 \u043d\u0430\u0439-\u0447\u0435\u0441\u0442\u0438\u0442\u0435 \u043d\u0435\u0436\u0435\u043b\u0430\u043d\u0438 \u0440\u0435\u0430\u043a\u0446\u0438\u0438 \u0432\u043a\u043b\u044e\u0447\u0432\u0430\u0442 \u043f\u0440\u0435\u0445\u043e\u0434\u043d\u0438 \u0441\u0442\u043e\u043c\u0430\u0448\u043d\u043e-\u0447\u0440\u0435\u0432\u043d\u0438 \u043f\u0440\u043e\u0431\u043b\u0435\u043c\u0438 [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8017323\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">41<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041d\u0430\u0439-\u0447\u0435\u0441\u0442\u0438\u0442\u0435 \u0441\u0442\u043e\u043c\u0430\u0448\u043d\u043e-\u0447\u0440\u0435\u0432\u043d\u0438 \u0440\u0435\u0430\u043a\u0446\u0438\u0438 \u0441\u0435 \u043f\u043e\u044f\u0432\u044f\u0432\u0430\u0442 \u043f\u0440\u0438 10-40% \u043e\u0442 \u0445\u043e\u0440\u0430\u0442\u0430, \u043f\u0440\u0438\u0435\u043c\u0430\u0449\u0438 3 \u043c\u0433\/\u0434\u0435\u043d \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0437\u0430 \u043e\u0442\u0441\u043b\u0430\u0431\u0432\u0430\u043d\u0435, \u0438 \u0432\u043a\u043b\u044e\u0447\u0432\u0430\u0442:<\/span><\/p><ul><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0433\u0430\u0434\u0435\u043d\u0435<\/span><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0434\u0438\u0430\u0440\u0438\u044f<\/span><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u043f\u043e\u0432\u0440\u044a\u0449\u0430\u043d\u0435<\/span><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0437\u0430\u043f\u0435\u043a<\/span><\/li><\/ul><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u043c\u043e\u0436\u0435 \u0441\u044a\u0449\u043e \u0442\u0430\u043a\u0430 \u0434\u0430 \u043f\u0440\u0438\u0447\u0438\u043d\u0438 \u0433\u043b\u0430\u0432\u043e\u0431\u043e\u043b\u0438\u0435, \u0443\u0441\u043a\u043e\u0440\u0435\u043d \u0441\u044a\u0440\u0434\u0435\u0447\u0435\u043d \u0440\u0438\u0442\u044a\u043c \u0438 \u0434\u0440\u0443\u0433\u0438 \u0441\u0442\u043e\u043c\u0430\u0448\u043d\u043e-\u0447\u0440\u0435\u0432\u043d\u0438 \u043f\u0440\u043e\u0431\u043b\u0435\u043c\u0438, \u043a\u043e\u0438\u0442\u043e \u0437\u0430\u0441\u044f\u0433\u0430\u0442 \u043e\u043a\u043e\u043b\u043e 10% \u043e\u0442 \u0445\u043e\u0440\u0430\u0442\u0430 [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.drugs.com\/sfx\/liraglutide-side-effects.html\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">42<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0412 \u0440\u0435\u0434\u043a\u0438 \u0441\u043b\u0443\u0447\u0430\u0438 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0438\u0442\u0435 \u043c\u043e\u0433\u0430\u0442 \u0434\u0430 \u043f\u043e\u043b\u0443\u0447\u0430\u0442 \u0430\u043b\u0435\u0440\u0433\u0438\u0447\u043d\u0438 \u0440\u0435\u0430\u043a\u0446\u0438\u0438 \u0438\u043b\u0438 \u043b\u043e\u043a\u0430\u043b\u043d\u0438 \u0440\u0435\u0430\u043a\u0446\u0438\u0438 \u043d\u0430 \u043c\u044f\u0441\u0442\u043e\u0442\u043e \u043d\u0430 \u0438\u043d\u0436\u0435\u043a\u0442\u0438\u0440\u0430\u043d\u0435, \u043a\u0430\u0442\u043e \u0431\u043e\u043b\u043a\u0430, \u043a\u044a\u0440\u0432\u0435\u043d\u0435, \u0437\u0430\u0447\u0435\u0440\u0432\u044f\u0432\u0430\u043d\u0435, \u043f\u043e\u0434\u0443\u0432\u0430\u043d\u0435 \u0438 \u0441\u044a\u0440\u0431\u0435\u0436.<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0420\u0435\u0434\u043a\u0438, \u043d\u043e \u043f\u043e-\u0441\u0435\u0440\u0438\u043e\u0437\u043d\u0438 \u0441\u0442\u0440\u0430\u043d\u0438\u0447\u043d\u0438 \u0435\u0444\u0435\u043a\u0442\u0438 \u043c\u043e\u0433\u0430\u0442 \u0434\u0430 \u0431\u044a\u0434\u0430\u0442 \u0445\u043e\u043b\u0435\u0441\u0442\u0430\u0437\u0430 \u0438 \u0441\u0432\u044a\u0440\u0437\u0430\u043d\u0438\u0442\u0435 \u0441 \u043d\u0435\u044f \u043f\u0430\u043d\u043a\u0440\u0435\u0430\u0442\u0438\u0442 \u0438\u043b\u0438 \u0437\u0430\u0431\u043e\u043b\u044f\u0432\u0430\u043d\u0435 \u043d\u0430 \u0436\u043b\u044a\u0447\u043d\u0438\u044f \u043c\u0435\u0445\u0443\u0440, \u043a\u043e\u0438\u0442\u043e \u0441\u0435 \u043f\u0440\u043e\u044f\u0432\u044f\u0432\u0430\u0442 \u0441\u044a\u0441 \u0441\u0438\u043b\u043d\u0430 \u043a\u043e\u0440\u0435\u043c\u043d\u0430 \u0431\u043e\u043b\u043a\u0430, \u043f\u043e\u0432\u0440\u044a\u0449\u0430\u043d\u0435, \u0442\u0440\u0435\u0441\u043a\u0430 \u0438 \u043f\u043e\u0436\u044a\u043b\u0442\u044f\u0432\u0430\u043d\u0435 \u043d\u0430 \u043a\u043e\u0436\u0430\u0442\u0430 \u0438\u043b\u0438 \u043e\u0447\u0438\u0442\u0435 [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25504028\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">43<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].<\/span><\/p><h2 dir=\"ltr\" style=\"line-height: 1.3800000000000001; margin-top: 18pt; margin-bottom: 6pt;\"><span style=\"font-size: 16pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0411\u0435\u0437\u043e\u043f\u0430\u0441\u043d\u0430 \u043b\u0438 \u0435 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430? | \u041f\u043e\u0441\u043b\u0435\u0434\u0441\u0442\u0432\u0438\u044f \u043e\u0442 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430<\/span><\/h2><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0435 \u043f\u0440\u0438\u0435\u0442 \u0437\u0430 \u0431\u0435\u0437\u043e\u043f\u0430\u0441\u0435\u043d \u0438 \u0435 \u043e\u0434\u043e\u0431\u0440\u0435\u043d \u043e\u0442 \u0415\u041c\u0410 \u0437\u0430 \u043b\u0435\u0447\u0435\u043d\u0438\u0435 \u043d\u0430 \u04222\u0414, \u043d\u0430\u0434\u043d\u043e\u0440\u043c\u0435\u043d\u043e \u0442\u0435\u0433\u043b\u043e \u0438 \u0437\u0430\u0442\u043b\u044a\u0441\u0442\u044f\u0432\u0430\u043d\u0435 \u043f\u0440\u0438 \u043b\u0438\u0446\u0430 \u043d\u0430 \u0432\u044a\u0437\u0440\u0430\u0441\u0442 \u043d\u0430\u0434 12 \u0433\u043e\u0434\u0438\u043d\u0438 \u0432\u044a\u0437 \u043e\u0441\u043d\u043e\u0432\u0430 \u043d\u0430 \u043c\u043d\u043e\u0436\u0435\u0441\u0442\u0432\u043e \u0434\u0430\u043d\u043d\u0438 \u043e\u0442 \u043a\u043b\u0438\u043d\u0438\u0447\u043d\u0438 \u0438\u0437\u043f\u0438\u0442\u0432\u0430\u043d\u0438\u044f.<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041f\u043e\u0441\u043b\u0435\u0434\u043d\u0438\u0442\u0435 \u043f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0438\u044f \u043f\u043e\u043a\u0430\u0437\u0432\u0430\u0442 \u0447\u0435 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u043a\u0430\u0442\u043e \u0446\u044f\u043b\u043e \u0441\u0435 \u043f\u043e\u043d\u0430\u0441\u044f \u0434\u043e\u0431\u0440\u0435 \u043e\u0442 \u043f\u043e\u0432\u0435\u0447\u0435\u0442\u043e \u0443\u0447\u0430\u0441\u0442\u043d\u0438\u0446\u0438 \u0432 \u043f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0438\u044f\u0442\u0430, \u0438 \u0441\u0442\u0440\u0430\u043d\u0438\u0447\u043d\u0438\u0442\u0435 \u0435\u0444\u0435\u043a\u0442\u0438 \u0441\u0430 \u0440\u044f\u0434\u043a\u043e\u0441\u0442 [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32127832\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">44<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].\u00a0<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0412\u044a\u043f\u0440\u0435\u043a\u0438 \u0442\u043e\u0432\u0430 \u0437\u0430\u0441\u043b\u0443\u0436\u0430\u0432\u0430 \u0434\u0430 \u0441\u0435 \u043e\u0442\u0431\u0435\u043b\u0435\u0436\u0438, \u0447\u0435 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u043d\u0435 \u0441\u0435 \u043f\u0440\u0435\u043f\u043e\u0440\u044a\u0447\u0432\u0430 \u0437\u0430 \u0431\u0440\u0435\u043c\u0435\u043d\u043d\u0438 \u0438 \u043a\u044a\u0440\u043c\u0430\u0447\u043a\u0438 \u043f\u043e\u0440\u0430\u0434\u0438 \u043d\u0435\u0438\u0437\u0432\u0435\u0441\u0442\u043d\u0438\u044f \u043f\u0440\u043e\u0444\u0438\u043b \u043d\u0430 \u0431\u0435\u0437\u043e\u043f\u0430\u0441\u043d\u043e\u0441\u0442 \u043d\u0430 \u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u043e\u0442\u043e \u043f\u0440\u0438 \u0442\u0435\u0437\u0438 \u0433\u0440\u0443\u043f\u0438.<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041e\u0441\u0432\u0435\u043d \u0442\u043e\u0432\u0430, \u043f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0438\u044f\u0442\u0430 \u043f\u0440\u0438 \u0436\u0438\u0432\u043e\u0442\u043d\u0438 \u043f\u043e\u043a\u0430\u0437\u0432\u0430\u0442 \u043f\u043e\u0442\u0435\u043d\u0446\u0438\u0430\u043b\u0435\u043d \u0440\u0438\u0441\u043a \u043e\u0442 \u0440\u0430\u043a \u043d\u0430 \u0449\u0438\u0442\u043e\u0432\u0438\u0434\u043d\u0430\u0442\u0430 \u0436\u043b\u0435\u0437\u0430, \u0441\u0432\u044a\u0440\u0437\u0430\u043d \u0441 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430.\u00a0<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0422\u043e\u0437\u0438 \u0440\u0438\u0441\u043a \u043e\u0431\u0430\u0447\u0435 \u043d\u0435 \u0435 \u043f\u043e\u0442\u0432\u044a\u0440\u0434\u0435\u043d \u043f\u0440\u0438 \u0438\u0437\u043f\u0438\u0442\u0432\u0430\u043d\u0438\u044f \u0432\u044a\u0440\u0445\u0443 \u0445\u043e\u0440\u0430, \u0432\u044a\u043f\u0440\u0435\u043a\u0438 \u0447\u0435 \u043a\u044a\u043c \u043c\u043e\u043c\u0435\u043d\u0442\u0430 \u043f\u0440\u0435\u043f\u0430\u0440\u0430\u0442\u0430 \u0441\u0435 \u0438\u0437\u043f\u043e\u043b\u0437\u0432\u0430 \u043e\u0442 \u0433\u043e\u0434\u0438\u043d\u0438, \u043f\u0440\u043e\u0432\u0435\u0434\u0435\u043d\u0438 \u0441\u0430 \u043f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0438\u044f \u0441\u0440\u0435\u0434 \u0434\u0435\u0441\u0435\u0442\u043a\u0438 \u0445\u0438\u043b\u044f\u0434\u0438 \u0445\u043e\u0440\u0430, \u0438 \u043c\u0435\u0434\u0438\u043a\u0430\u043c\u0435\u043d\u0442\u0430 \u0435 \u043f\u043e\u0434 \u0430\u043a\u0442\u0438\u0432\u043d\u043e \u043d\u0430\u0431\u043b\u044e\u0434\u0435\u043d\u0438\u0435 \u043e\u0442 \u0415\u041c\u0410 \u0437\u0430 \u0432\u044a\u0437\u043c\u043e\u0436\u043d\u0438 \u0441\u0442\u0440\u0430\u043d\u0438\u0447\u043d\u0438 \u0435\u0444\u0435\u043a\u0442\u0438 \u0441\u0440\u0435\u0434 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0438\u0442\u0435 \u043d\u0430 \u043a\u043e\u0438\u0442\u043e \u0441\u0435 \u043f\u0440\u0435\u0434\u043f\u0438\u0441\u0432\u0430 [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8203194\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">45<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">]. <\/span><\/p><h2 dir=\"ltr\" style=\"line-height: 1.38; margin-top: 18pt; margin-bottom: 6pt;\"><span style=\"font-size: 16pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041a\u0430\u043a \u0441\u0435 \u0441\u043b\u0430\u0433\u0430 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 | \u0414\u043e\u0437\u0438\u0440\u043e\u0432\u043a\u0430 \u043f\u043e \u0441\u0445\u0435\u043c\u0430<\/span><\/h2><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041c\u0430\u043a\u0441\u0438\u043c\u0430\u043b\u043d\u0430\u0442\u0430 \u043f\u0440\u0435\u043f\u043e\u0440\u044a\u0447\u0438\u0442\u0435\u043b\u043d\u0430 \u0434\u043e\u0437\u0430 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0437\u0430 \u043e\u0442\u0441\u043b\u0430\u0431\u0432\u0430\u043d\u0435 \u0435 3 \u043c\u0433\/\u0434\u0435\u043d, \u043d\u043e \u0442\u044f \u043c\u043e\u0436\u0435 \u0434\u0430 \u0431\u044a\u0434\u0435 \u043a\u043e\u0440\u0438\u0433\u0438\u0440\u0430\u043d\u0430 \u0432 \u0437\u0430\u0432\u0438\u0441\u0438\u043c\u043e\u0441\u0442 \u043e\u0442 \u0438\u043d\u0434\u0438\u0432\u0438\u0434\u0443\u0430\u043b\u043d\u0430\u0442\u0430 \u043f\u043e\u043d\u043e\u0441\u0438\u043c\u043e\u0441\u0442 [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8307742\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">46<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">]. \u0417\u0430 \u0441\u043f\u0440\u0430\u0432\u043a\u0430, \u043f\u0440\u0435\u043f\u043e\u0440\u044a\u0447\u0438\u0442\u0435\u043b\u043d\u0430\u0442\u0430 \u0434\u043e\u0437\u0430 \u0412\u0438\u043a\u0442\u043e\u0437\u0430 \u0437\u0430 \u043b\u0435\u0447\u0435\u043d\u0438\u0435 \u043d\u0430 \u04222\u0414 \u0435 \u0434\u043e 1,8 \u043c\u0433\/\u0434\u0435\u043d [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27350545\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">26<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041f\u0440\u0435\u043f\u043e\u0440\u044a\u0447\u0432\u0430 \u0441\u0435 \u0442\u0435\u0440\u0430\u043f\u0438\u044f\u0442\u0430 \u0434\u0430 \u0437\u0430\u043f\u043e\u0447\u043d\u0435 \u0441 \u043d\u0438\u0441\u043a\u0430 \u0434\u043d\u0435\u0432\u043d\u0430 \u0434\u043e\u0437\u0430 \u043e\u0442 0,6 \u043c\u0433\/\u0434\u0435\u043d \u0438 \u043f\u043e\u0441\u0442\u0435\u043f\u0435\u043d\u043d\u043e \u0434\u0430 \u0441\u0435 \u0443\u0432\u0435\u043b\u0438\u0447\u0430\u0432\u0430\u0442 \u0441 \u043f\u043e 0,6 \u043c\u0433 \u0432 \u043f\u0440\u043e\u0434\u044a\u043b\u0436\u0435\u043d\u0438\u0435 \u043d\u0430 \u043f\u0435\u0442 \u0441\u0435\u0434\u043c\u0438\u0446\u0438. \u0422\u043e\u0432\u0430 \u0441\u043f\u043e\u043c\u0430\u0433\u0430 \u0437\u0430 \u043d\u0430\u043c\u0430\u043b\u044f\u0432\u0430\u043d\u0435 \u043d\u0430 \u0441\u0442\u0440\u0430\u043d\u0438\u0447\u043d\u0438\u0442\u0435 \u0435\u0444\u0435\u043a\u0442\u0438 \u0441\u0440\u0435\u0434 \u0443\u0447\u0430\u0441\u0442\u043d\u0438\u0446\u0438\u0442\u0435 \u0432 \u0438\u0437\u0441\u043b\u0435\u0434\u0432\u0430\u043d\u0435\u0442\u043e.<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041e\u0441\u0432\u0435\u043d \u0442\u043e\u0432\u0430 \u043f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0438\u044f\u0442\u0430 \u0441\u043e\u0447\u0430\u0442, \u0447\u0435 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u043c\u043e\u0436\u0435 \u0434\u0430 \u0441\u0435 \u043f\u0440\u0438\u043b\u0430\u0433\u0430 \u043f\u0440\u043e\u0434\u044a\u043b\u0436\u0438\u0442\u0435\u043b\u043d\u043e \u0432\u0440\u0435\u043c\u0435 \u0432 \u0434\u043e\u0437\u0430 3,0 \u043c\u0433\/\u0434\u0435\u043d, \u043a\u0430\u0442\u043e \u043f\u0435\u043f\u0442\u0438\u0434\u044a\u0442 \u043d\u0435 \u0442\u0440\u044f\u0431\u0432\u0430 \u0434\u0430 \u0441\u0435 \u0446\u0438\u043a\u043b\u0438\u0437\u0438\u0440\u0430. \u0412\u043c\u0435\u0441\u0442\u043e \u0442\u043e\u0432\u0430 \u043f\u0443\u0431\u043b\u0438\u043a\u0443\u0432\u0430\u043d\u0438\u0442\u0435 \u0438\u0437\u0441\u043b\u0435\u0434\u0432\u0430\u043d\u0438\u044f \u0440\u0430\u0437\u043a\u0440\u0438\u0432\u0430\u0442, \u0447\u0435 \u043d\u0430\u0439-\u0447\u0435\u0441\u0442\u043e \u0441\u0440\u0435\u0449\u0430\u043d\u0438\u0442\u0435 \u043f\u0440\u043e\u0442\u043e\u043a\u043e\u043b\u0438 \u0437\u0430 \u0434\u043e\u0437\u0438\u0440\u0430\u043d\u0435 \u0441\u0430 \u0441 \u043f\u0440\u043e\u0434\u044a\u043b\u0436\u0438\u0442\u0435\u043b\u043d\u043e\u0441\u0442 20-68 \u0441\u0435\u0434\u043c\u0438\u0446\u0438 [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9738168\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">37<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">].<\/span><\/p><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0415\u0442\u043e \u043f\u0440\u0438\u043c\u0435\u0440\u0435\u043d \u043f\u0440\u043e\u0442\u043e\u043a\u043e\u043b \u0437\u0430 \u0434\u043e\u0437\u0438\u0440\u0430\u043d\u0435 \u043d\u0430 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0437\u0430 \u0438\u0437\u0441\u043b\u0435\u0434\u0432\u0430\u043d\u0435 \u043d\u0430 \u043e\u0442\u0441\u043b\u0430\u0431\u0432\u0430\u043d\u0435\u0442\u043e \u0432\u044a\u0437 \u043e\u0441\u043d\u043e\u0432\u0430 \u043d\u0430 \u043f\u0443\u0431\u043b\u0438\u043a\u0443\u0432\u0430\u043d\u0438\u0442\u0435 \u0434\u0430\u043d\u043d\u0438 [<\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9738168\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">37<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">, <\/span><a style=\"text-decoration: none;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5358074\/\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #1155cc; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: underline; -webkit-text-decoration-skip: none; text-decoration-skip-ink: none; vertical-align: baseline; white-space: pre-wrap;\">47<\/span><\/a><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">]:\u00a0<\/span><\/p><ul><li><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: bold; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0414\u043e\u0437\u0430 \u043d\u0430 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430<\/span><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">: \u0417\u0430\u043f\u043e\u0447\u043d\u0435\u0442\u0435 \u0441 0,6 \u043c\u0433\/\u0434\u043d\u0435\u0432\u043d\u043e \u043f\u0440\u0435\u0437 \u043f\u044a\u0440\u0432\u0430\u0442\u0430 \u0441\u0435\u0434\u043c\u0438\u0446\u0430, \u043f\u043e\u0441\u043b\u0435\u0434\u0432\u0430\u043d\u043e \u043e\u0442 \u0443\u0432\u0435\u043b\u0438\u0447\u0435\u043d\u0438\u0435 \u0434\u043e 1,2 \u043c\u0433\/\u0434\u043d\u0435\u0432\u043d\u043e \u043f\u0440\u0435\u0437 \u0432\u0442\u043e\u0440\u0430\u0442\u0430 \u0441\u0435\u0434\u043c\u0438\u0446\u0430, 1,8 \u043c\u0433\/\u0434\u043d\u0435\u0432\u043d\u043e \u043f\u0440\u0435\u0437 \u0442\u0440\u0435\u0442\u0430\u0442\u0430 \u0441\u0435\u0434\u043c\u0438\u0446\u0430, 2,4 \u043c\u0433\/\u0434\u043d\u0435\u0432\u043d\u043e \u043f\u0440\u0435\u0437 \u0447\u0435\u0442\u0432\u044a\u0440\u0442\u0430\u0442\u0430 \u0441\u0435\u0434\u043c\u0438\u0446\u0430 \u0438 3,0 \u043c\u0433\/\u0434\u043d\u0435\u0432\u043d\u043e \u043f\u0440\u0435\u0437 \u043f\u0435\u0442\u0430\u0442\u0430 \u0438 \u0441\u043b\u0435\u0434\u0432\u0430\u0449\u0438\u0442\u0435 \u0441\u0435\u0434\u043c\u0438\u0446\u0438.<\/span><\/li><li><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: bold; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0427\u0435\u0441\u0442\u043e\u0442\u0430 \u043d\u0430 \u0434\u043e\u0437\u0438\u0440\u0430\u043d\u0435<\/span><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">: \u0412\u0435\u0434\u043d\u044a\u0436 \u0434\u043d\u0435\u0432\u043d\u043e \u0432 \u0440\u0435\u0434\u043e\u0432\u043d\u0438 \u0447\u0430\u0441\u043e\u0432\u0435.<\/span><\/li><li><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: bold; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041f\u0440\u043e\u0434\u044a\u043b\u0436\u0438\u0442\u0435\u043b\u043d\u043e\u0441\u0442<\/span><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">: 20-68 \u0441\u0435\u0434\u043c\u0438\u0446\u0438.<\/span><\/li><li><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: bold; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0417\u0430\u0431\u0435\u043b\u0435\u0436\u043a\u0438<\/span><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">: \u0414\u043d\u0435\u0432\u043d\u0430\u0442\u0430 \u0434\u043e\u0437\u0430 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u043d\u0438\u043a\u043e\u0433\u0430 \u043d\u0435 \u0442\u0440\u044f\u0431\u0432\u0430 \u0434\u0430 \u043d\u0430\u0434\u0432\u0438\u0448\u0430\u0432\u0430 3\u043c\u0433\/\u0434\u0435\u043d.<\/span><\/li><\/ul><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u043c\u043e\u0436\u0435 \u0434\u0430 \u0441\u0435 \u0438\u043d\u0436\u0435\u043a\u0442\u0438\u0440\u0430 \u043f\u043e \u0432\u0441\u044f\u043a\u043e \u0432\u0440\u0435\u043c\u0435 \u043e\u0442 \u0434\u0435\u043d\u043e\u043d\u043e\u0449\u0438\u0435\u0442\u043e, \u0431\u0435\u0437 \u0437\u043d\u0430\u0447\u0435\u043d\u0438\u0435 \u043e\u0442 \u0445\u0440\u0430\u043d\u0435\u043d\u0435\u0442\u043e \u0412\u0438.<\/span><\/p><p><img decoding=\"async\" class=\"alignnone size-full wp-image-5138\" src=\"https:\/\/drmarinov.com\/wp-content\/uploads\/2024\/02\/cId53jVk.png\" alt=\"\u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u043f\u043e\u0441\u043b\u0435\u0434\u0441\u0442\u0432\u0438\u044f\" width=\"1476\" height=\"229\" srcset=\"https:\/\/drmarinov.com\/wp-content\/uploads\/2024\/02\/cId53jVk.png 1476w, https:\/\/drmarinov.com\/wp-content\/uploads\/2024\/02\/cId53jVk-300x47.png 300w, https:\/\/drmarinov.com\/wp-content\/uploads\/2024\/02\/cId53jVk-1024x159.png 1024w, https:\/\/drmarinov.com\/wp-content\/uploads\/2024\/02\/cId53jVk-768x119.png 768w, https:\/\/drmarinov.com\/wp-content\/uploads\/2024\/02\/cId53jVk-18x3.png 18w\" sizes=\"(max-width: 1476px) 100vw, 1476px\" \/><\/p><h2><span style=\"font-size: 16pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0415\u0444\u0435\u043a\u0442\u0438\u0432\u043d\u0430 \u0438 \u0431\u0435\u0437\u043e\u043f\u0430\u0441\u043d\u0430 \u043b\u0438 \u0435 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0437\u0430 \u043e\u0442\u0441\u043b\u0430\u0431\u0432\u0430\u043d\u0435 \u043f\u0440\u0438 \u043d\u0430\u0434\u043d\u043e\u0440\u043c\u0435\u043d\u043e \u0442\u0435\u0433\u043b\u043e \u0438 \u0437\u0430\u0442\u043b\u044a\u0441\u0442\u044f\u0432\u0430\u043d\u0435? \u041c\u043d\u0435\u043d\u0438\u0435 \u043d\u0430 \u043b\u0435\u043a\u0430\u0440:<\/span><\/h2><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u201e<\/span><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: italic; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041a\u043e\u0433\u0430\u0442\u043e \u0441\u0435 \u043f\u0440\u0438\u043b\u0430\u0433\u0430 \u0441\u043f\u043e\u0440\u0435\u0434 \u043b\u0435\u043a\u0430\u0440\u0441\u043a\u043e \u043f\u0440\u0435\u0434\u043f\u0438\u0441\u0430\u043d\u0438\u0435 \u0438 \u043f\u043e\u0434 \u0441\u0442\u0440\u043e\u0433\u043e\u0442\u043e \u043d\u0430\u0431\u043b\u044e\u0434\u0435\u043d\u0438\u0435 \u043d\u0430 \u0441\u043f\u0435\u0446\u0438\u0430\u043b\u0438\u0441\u0442, \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0435 \u0435\u0444\u0438\u043a\u0430\u0441\u0435\u043d \u0438\u043d\u0441\u0442\u0440\u0443\u043c\u0435\u043d\u0442 \u0437\u0430 \u043d\u0430\u043c\u0430\u043b\u044f\u0432\u0430\u043d\u0435 \u043d\u0430 \u0430\u043f\u0435\u0442\u0438\u0442\u0430 \u0438 \u043f\u043e\u043c\u0430\u0433\u0430 \u0432 \u0431\u043e\u0440\u0431\u0430\u0442\u0430 \u0441 \u043d\u0430\u0434\u043d\u043e\u0440\u043c\u0435\u043d\u043e\u0442\u043e \u0442\u0435\u0433\u043b\u043e \u0438 \u0437\u0430\u0442\u043b\u044a\u0441\u0442\u044f\u0432\u0430\u043d\u0435\u0442\u043e. \u0412\u044a\u0437\u043c\u043e\u0436\u043d\u0438\u0442\u0435 \u0441\u0442\u0440\u0430\u043d\u0438\u0447\u043d\u0438 \u0435\u0444\u0435\u043a\u0442\u0438 \u043c\u043e\u0433\u0430\u0442 \u0434\u0430 \u0431\u044a\u0434\u0430\u0442 \u0443\u043f\u0440\u0430\u0432\u043b\u044f\u0435\u043c\u0438 \u0441 \u043f\u0440\u0430\u0432\u0438\u043b\u043d\u043e\u0442\u043e \u0434\u043e\u0437\u0438\u0440\u0430\u043d\u0435. \u0427\u0435\u0441\u0442\u043e \u0441\u0440\u0435\u0449\u0430\u043d\u0438\u0442\u0435 \u043d\u0435\u0436\u0435\u043b\u0430\u043d\u0438 \u0440\u0435\u0430\u043a\u0446\u0438\u0438 \u0432\u043a\u043b\u044e\u0447\u0432\u0430\u0442 \u0441\u0442\u043e\u043c\u0430\u0448\u043d\u043e-\u0447\u0440\u0435\u0432\u043d\u0438 \u043f\u0440\u043e\u0431\u043b\u0435\u043c\u0438, \u043e\u0441\u043e\u0431\u0435\u043d\u043e \u0433\u0430\u0434\u0435\u043d\u0435, \u043a\u043e\u0438\u0442\u043e \u043e\u0431\u0438\u043a\u043d\u043e\u0432\u0435\u043d\u043e \u0441\u0430 \u043d\u0430\u0439-\u0438\u0437\u0440\u0430\u0437\u0435\u043d\u0438 \u0432 \u043d\u0430\u0447\u0430\u043b\u043e\u0442\u043e \u043d\u0430 \u043b\u0435\u0447\u0435\u043d\u0438\u0435\u0442\u043e \u0438 \u0442\u0435\u043d\u0434\u0435\u043d\u0446\u0438\u043e\u0437\u043d\u043e \u043d\u0430\u043c\u0430\u043b\u044f\u0432\u0430\u0442 \u0438\u043b\u0438 \u0438\u0437\u0447\u0435\u0437\u0432\u0430\u0442 \u0432 \u0440\u0430\u043c\u043a\u0438\u0442\u0435 \u043d\u0430 \u043d\u044f\u043a\u043e\u043b\u043a\u043e \u043c\u0435\u0441\u0435\u0446\u0430. \u041b\u0438\u0446\u0430 \u0441 \u043f\u0440\u0435\u0434\u0440\u0430\u0437\u043f\u043e\u043b\u043e\u0436\u0435\u043d\u0438\u0435 \u043a\u044a\u043c \u043f\u0430\u043d\u043a\u0440\u0435\u0430\u0442\u0438\u0442 \u0438\u043b\u0438 \u0436\u043b\u044a\u0447\u043d\u043e\u043a\u0430\u043c\u0435\u043d\u043d\u0430 \u0431\u043e\u043b\u0435\u0441\u0442 \u043c\u043e\u0433\u0430\u0442 \u0434\u0430 \u0431\u044a\u0434\u0430\u0442 \u0438\u0437\u043b\u043e\u0436\u0435\u043d\u0438 \u043d\u0430 \u043f\u043e-\u0432\u0438\u0441\u043e\u043a \u0440\u0438\u0441\u043a \u043e\u0442 \u0441\u0435\u0440\u0438\u043e\u0437\u043d\u0438 \u0443\u0441\u043b\u043e\u0436\u043d\u0435\u043d\u0438\u044f, \u043a\u043e\u0435\u0442\u043e \u043d\u0430\u043b\u0430\u0433\u0430 \u0440\u0435\u0433\u0443\u043b\u044f\u0440\u043d\u043e \u043f\u0440\u043e\u0441\u043b\u0435\u0434\u044f\u0432\u0430\u043d\u0435 \u043e\u0442 \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0438 \u0441\u043f\u0435\u0446\u0438\u0430\u043b\u0438\u0441\u0442. \u0412\u044a\u043f\u0440\u0435\u043a\u0438 \u043f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0438\u044f\u0442\u0430 \u0441 \u0436\u0438\u0432\u043e\u0442\u043d\u0438, \u0438\u0437\u0441\u043b\u0435\u0434\u0432\u0430\u043d\u0438\u044f\u0442\u0430 \u043f\u0440\u0438 \u0445\u043e\u0440\u0430 \u043d\u0435 \u043f\u043e\u043a\u0430\u0437\u0432\u0430\u0442 \u0440\u0438\u0441\u043a \u043e\u0442 \u0440\u0430\u043a \u0438\u043b\u0438 \u0434\u0440\u0443\u0433\u0438 \u0441\u0435\u0440\u0438\u043e\u0437\u043d\u0438 \u0441\u0442\u0440\u0430\u043d\u0438\u0447\u043d\u0438 \u0435\u0444\u0435\u043a\u0442\u0438.<\/span><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u201c<\/span><\/p><h2 dir=\"ltr\" style=\"line-height: 1.38; margin-top: 18pt; margin-bottom: 6pt;\"><span style=\"font-size: 16pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0427\u0435\u0441\u0442\u043e \u0437\u0430\u0434\u0430\u0432\u0430\u043d\u0438 \u0412\u044a\u043f\u0440\u043e\u0441\u0438 (FAQ)<\/span><\/h2><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0412 \u0441\u043b\u0435\u0434\u0432\u0430\u0449\u0438\u0442\u0435 \u0440\u0435\u0434\u043e\u0432\u0435 \u0449\u0435 \u043e\u0442\u0433\u043e\u0432\u043e\u0440\u0438\u043c \u043d\u0430 \u043d\u044f\u043a\u043e\u0438 \u043e\u0442 \u043d\u0430\u0439-\u0447\u0435\u0441\u0442\u043e \u0437\u0430\u0434\u0430\u0432\u0430\u043d\u0438\u0442\u0435 \u0432\u044a\u043f\u0440\u043e\u0441\u0438 \u043e\u0442 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0438 \u0437\u0430 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430<\/span><\/p><h3 dir=\"ltr\" style=\"line-height: 1.38; margin-top: 16pt; margin-bottom: 4pt;\"><span style=\"font-size: 13.999999999999998pt; font-family: Arial,sans-serif; color: #434343; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0421\u044a\u0449\u0435\u0441\u0442\u0432\u0443\u0432\u0430\u0442 \u043b\u0438 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0442\u0430\u0431\u043b\u0435\u0442\u043a\u0438?<\/span><\/h3><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041d\u0435, \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0441\u044a\u0434\u044a\u0440\u0436\u0430 \u043f\u0435\u043f\u0442\u0438\u0434 \u043d\u0430\u0440\u0435\u0447\u0435\u043d \u043b\u0438\u0440\u0430\u0433\u043b\u0443\u0442\u0438\u0434 \u043a\u043e\u0439\u0442\u043e \u0431\u044a\u0440\u0437\u043e \u0441\u0435 \u0440\u0430\u0437\u0440\u0443\u0448\u0430\u0432\u0430 \u043e\u0442 \u0435\u043d\u0437\u0438\u043c\u0438\u0442\u0435 \u0438 \u043a\u0438\u0441\u0435\u043b\u0438\u043d\u0438\u0442\u0435 \u0432 \u0441\u0442\u043e\u043c\u0430\u0445\u0430, \u0438 \u043d\u0435 \u0435 \u0435\u0444\u0435\u043a\u0442\u0438\u0432\u0435\u043d \u043f\u0440\u0438 \u043f\u0440\u0438\u0435\u043c \u043d\u0430 \u0442\u0430\u0431\u043b\u0435\u0442\u043a\u0438.<\/span><\/p><h3 dir=\"ltr\" style=\"line-height: 1.38; margin-top: 16pt; margin-bottom: 4pt;\"><span style=\"font-size: 13.999999999999998pt; font-family: Arial,sans-serif; color: #434343; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0418\u043c\u0430 \u043b\u0438 \u0435\u0441\u0442\u0435\u0441\u0442\u0432\u0435\u043d \u0437\u0430\u043c\u0435\u0441\u0442\u0438\u0442\u0435\u043b \u043d\u0430 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430?<\/span><\/h3><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041d\u0435, \u043d\u044f\u043c\u0430 \u0434\u043e\u0431\u0430\u0432\u043a\u0438 \u0438\u043b\u0438 \u0445\u0440\u0430\u043d\u0438\u0442\u0435\u043b\u043d\u0438 \u0432\u0435\u0449\u0435\u0441\u0442\u0432\u0430 \u043a\u043e\u0438\u0442\u043e \u0434\u0430 \u0438\u043c\u0438\u0442\u0438\u0440\u0430\u0442 \u0444\u0443\u043d\u043a\u0446\u0438\u044f\u0442\u0430 \u043d\u0430 \u0438\u043d\u043a\u0440\u0435\u0442\u0438\u043d\u043e\u0432\u0438\u0442\u0435 \u0445\u043e\u0440\u043c\u043e\u043d\u0438 \u0442\u0430\u043a\u0430 \u043a\u0430\u043a\u0442\u043e \u0433\u043e \u043f\u0440\u0430\u0432\u044f\u0442 \u043c\u0435\u0434\u0438\u043a\u0430\u043c\u0435\u043d\u0442\u0438\u0442\u0435 \u043e\u0442 \u0433\u0440\u0443\u043f\u0430\u0442\u0430 \u043d\u0430 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430.<\/span><\/p><h3 dir=\"ltr\" style=\"line-height: 1.38; margin-top: 16pt; margin-bottom: 4pt;\"><span style=\"font-size: 13.999999999999998pt; font-family: Arial,sans-serif; color: #434343; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041a\u0430\u043a\u0432\u043e \u0435 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u043f\u0435\u043d?<\/span><\/h3><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u043f\u0435\u043d (Saxenda pen) \u0435 \u0443\u0441\u0442\u0440\u043e\u0439\u0441\u0442\u0432\u043e\u0442\u043e \u043a\u043e\u0435\u0442\u043e \u0441\u044a\u0434\u044a\u0440\u0436\u0430 \u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u043e\u0442\u043e. \u0422\u043e \u043f\u0440\u0435\u0434\u0441\u0442\u0430\u0432\u043b\u044f\u0432\u0430 \u043f\u0438\u0441\u0430\u043b\u043a\u0430, \u043f\u043e\u0434\u043e\u0431\u043d\u0430 \u043d\u0430 \u0442\u0435\u0437\u0438 \u0437\u0430 \u0438\u043d\u0436\u0435\u043a\u0442\u0438\u0440\u0430\u043d\u0435 \u043d\u0430 \u0438\u043d\u0441\u0443\u043b\u0438\u043d. \u0422\u044f \u043c\u043e\u0436\u0435 \u0434\u0430 \u0441\u0435 \u043d\u0430\u0441\u0442\u0440\u043e\u0439\u0432\u0430 \u043d\u0430 \u0434\u043e\u0437\u0438 \u043e\u0442 0.6 \u0434\u043e 3 \u043c\u0433. \u0420\u0430\u0431\u043e\u0442\u0438 \u0441 \u043c\u043d\u043e\u0433\u043e \u043c\u0430\u043b\u043a\u0438 \u0438 \u0442\u044a\u043d\u043a\u0438 \u0438\u0433\u043b\u0438 \u0437\u0430 \u043f\u043e\u0434\u043a\u043e\u0436\u043d\u043e \u0438\u043d\u0436\u0435\u043a\u0442\u0438\u0440\u0430\u043d\u0435, \u043a\u043e\u0438\u0442\u043e \u0441\u0435 \u043f\u0440\u043e\u0434\u0430\u0432\u0430\u0442 \u043e\u0442\u0434\u0435\u043b\u043d\u043e.<\/span><\/p><p dir=\"ltr\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-5351\" src=\"https:\/\/drmarinov.com\/wp-content\/uploads\/2024\/04\/image-47.jpg\" alt=\"\u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430\" width=\"260\" height=\"623\" srcset=\"https:\/\/drmarinov.com\/wp-content\/uploads\/2024\/04\/image-47.jpg 260w, https:\/\/drmarinov.com\/wp-content\/uploads\/2024\/04\/image-47-125x300.jpg 125w, https:\/\/drmarinov.com\/wp-content\/uploads\/2024\/04\/image-47-5x12.jpg 5w\" sizes=\"(max-width: 260px) 100vw, 260px\" \/><\/p><h3 dir=\"ltr\" style=\"line-height: 1.38; margin-top: 16pt; margin-bottom: 4pt;\"><span style=\"font-size: 13.999999999999998pt; font-family: Arial,sans-serif; color: #434343; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0418\u043d\u0441\u0443\u043b\u0438\u043d\u043e\u0432\u0438 \u0438\u043d\u0436\u0435\u043a\u0446\u0438\u0438 \u0437\u0430 \u043e\u0442\u0441\u043b\u0430\u0431\u0432\u0430\u043d\u0435 \u043b\u0438 \u0441\u0430 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430?<\/span><\/h3><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041d\u0435\u043f\u0440\u0430\u0432\u0438\u043b\u043d\u043e \u0435 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0438 \u043f\u043e\u0434\u043e\u0431\u043d\u0438 \u043c\u0435\u0434\u0438\u043a\u0430\u043c\u0435\u043d\u0442\u0438 \u0434\u0430 \u0441\u0435 \u043d\u0430\u0440\u0438\u0447\u0430\u0442 \u0438\u043d\u0441\u0443\u043b\u0438\u043d\u043e\u0432\u0438 \u0438\u043d\u0436\u0435\u043a\u0446\u0438\u0438. \u0422\u0435 \u043d\u0435 \u0441\u044a\u0434\u044a\u0440\u0436\u0430\u0442 \u0438\u043d\u0441\u0443\u043b\u0438\u043d, \u0438 \u0441\u0442\u0438\u043c\u0443\u043b\u0438\u0440\u0430\u0442 \u043f\u043e\u0432\u0438\u0448\u0435\u043d\u043e \u043e\u0442\u0434\u0435\u043b\u044f\u043d\u0435 \u043d\u0430 \u0438\u043d\u0441\u0443\u043b\u0438\u043d \u043e\u0442 \u043f\u0430\u043d\u043a\u0440\u0435\u0430\u0441\u0430 \u0441\u0430\u043c\u043e \u043a\u043e\u0433\u0430\u0442\u043e \u043a\u0440\u044a\u0432\u043d\u0430\u0442\u0430 \u0437\u0430\u0445\u0430\u0440 \u0435 \u0432\u0438\u0441\u043e\u043a\u0430.<\/span><\/p><h3 dir=\"ltr\" style=\"line-height: 1.38; margin-top: 16pt; margin-bottom: 4pt;\"><span style=\"font-size: 13.999999999999998pt; font-family: Arial,sans-serif; color: #434343; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u041a\u0430\u043a\u0432\u0430 \u0435 \u0446\u0435\u043d\u0430\u0442\u0430 \u043d\u0430 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0432 \u0411\u044a\u043b\u0433\u0430\u0440\u0438\u044f?<\/span><\/h3><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0426\u0435\u043d\u0430\u0442\u0430 \u043d\u0430 \u0435\u0434\u043d\u0430 \u043e\u043f\u0430\u043a\u043e\u0432\u043a\u0430 \u0441\u044a\u0434\u044a\u0440\u0436\u0430\u0449\u0430 3 \u043f\u0438\u0441\u0430\u043b\u043a\u0438 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0435 \u043e\u043a\u043e\u043b\u043e 250-300\u043b\u0432. \u0412\u0441\u044f\u043a\u0430 \u043f\u0438\u0441\u0430\u043b\u043a\u0430 \u0441\u044a\u0434\u044a\u0440\u0436\u0430 18\u043c\u0433 \u043e\u0442 \u043f\u0435\u043f\u0442\u0438\u0434\u0430 \u0438 \u0435 \u0434\u043e\u0441\u0442\u0430\u0442\u044a\u0447\u043d\u0430 \u0437\u0430 6 \u0434\u043e\u0437\u0438 \u043f\u043e 3\u043c\u0433. \u0421 \u0434\u0440\u0443\u0433\u0438 \u0434\u0443\u043c\u0438 \u0432\u0441\u044f\u043a\u0430 \u043e\u043f\u0430\u043a\u043e\u0432\u043a\u0430 (3 \u043f\u0438\u0441\u0430\u043b\u043a\u0438) \u0441\u044a\u0434\u044a\u0440\u0436\u0430 \u043e\u0431\u0449\u043e 18 \u0434\u043e\u0437\u0438 \u043e\u0442 3\u043c\u0433, \u043d\u043e \u0430\u043a\u043e \u043e\u0441\u0442\u0430\u043d\u0435\u0442\u0435 \u043d\u0430 \u043f\u043e-\u043d\u0438\u0441\u043a\u0430 \u0434\u043e\u0437\u0430, \u0431\u0440\u043e\u044f \u043d\u0430 \u0434\u043e\u0437\u0438\u0442\u0435 \u043f\u0440\u043e\u043f\u043e\u0440\u0446\u0438\u043e\u043d\u0430\u043b\u043d\u043e \u0441\u0435 \u0443\u0432\u0435\u043b\u0438\u0447\u0430\u0432\u0430 (\u0434\u043e 90 \u0434\u043e\u0437\u0438 \u043f\u0440\u0438 0.6\u043c\u0433\/\u0434\u0435\u043d).<\/span><\/p><h3 dir=\"ltr\" style=\"line-height: 1.38; margin-top: 16pt; margin-bottom: 4pt;\"><span style=\"font-size: 13.999999999999998pt; font-family: Arial,sans-serif; color: #434343; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0417\u0430 \u043a\u043e\u043b\u043a\u043e \u0432\u0440\u0435\u043c\u0435 \u0449\u0435 \u043c\u0438 \u0441\u0442\u0438\u0433\u043d\u0435 \u0435\u0434\u043d\u0430 \u043e\u043f\u0430\u043a\u043e\u0432\u043a\u0430 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430?<\/span><\/h3><p dir=\"ltr\" style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 10pt;\"><span style=\"font-size: 12pt; font-family: Arial,sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">\u0422\u0435\u0440\u0430\u043f\u0438\u044f\u0442\u0430 \u0441\u044a\u0441 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u0437\u0430\u043f\u043e\u0447\u0432\u0430 \u0441 \u043c\u043d\u043e\u0433\u043e \u043f\u043e-\u043c\u0430\u043b\u043a\u0430\u0442\u0430 \u0434\u043e\u0437\u0430 \u043e\u0442 0.6 \u043c\u0433\/\u0434\u0435\u043d \u043a\u043e\u044f\u0442\u043e \u043f\u043e\u0441\u0442\u0435\u043f\u0435\u043d\u043d\u043e \u0441\u0435 \u0443\u0432\u0435\u043b\u0438\u0447\u0430\u0432\u0430 \u0432 \u0440\u0430\u043c\u043a\u0438\u0442\u0435 \u043d\u0430 \u043c\u0438\u043d\u0438\u043c\u0443\u043c \u0447\u0435\u0442\u0438\u0440\u0438 \u0441\u0435\u0434\u043c\u0438\u0446\u0438. \u0415\u0434\u043d\u0430 \u043e\u043f\u0430\u043a\u043e\u0432\u043a\u0430 \u0435 \u043d\u0430\u043f\u044a\u043b\u043d\u043e \u0434\u043e\u0441\u0442\u0430\u0442\u044a\u0447\u043d\u0430 \u0437\u0430 \u043f\u044a\u0440\u0432\u0438\u0442\u0435 \u0447\u0435\u0442\u0438\u0440\u0438 \u0441\u0435\u0434\u043c\u0438\u0446\u0438 \u043e\u0442 \u0442\u0435\u0440\u0430\u043f\u0438\u044f\u0442\u0430 (+ \u0449\u0435 \u043e\u0441\u0442\u0430\u043d\u0430\u0442 \u043e\u0449\u0435 4 \u0434\u043e\u0437\u0438 \u043f\u043e 3 \u043c\u0433\/\u0434\u0435\u043d), \u0441\u043b\u0435\u0434 \u043a\u043e\u0435\u0442\u043e \u0449\u0435 \u0441\u0435 \u043d\u0443\u0436\u0434\u0430\u0435\u0442\u0435 \u043e\u0442 \u043d\u043e\u0432\u0430 \u043e\u043f\u0430\u043a\u043e\u0432\u043a\u0430 \u043d\u0430 \u0432\u0441\u0435\u043a\u0438 18 \u0434\u043d\u0438. \u0412 \u0434\u0435\u0439\u0441\u0442\u0432\u0438\u0442\u0435\u043b\u043d\u043e\u0441\u0442 \u0421\u0430\u043a\u0441\u0435\u043d\u0434\u0430 \u043c\u043e\u0436\u0435 \u0434\u0430 \u0441\u0435 \u0434\u043e\u0437\u0438\u0440\u0430 \u0438 \u043c\u043d\u043e\u0433\u043e \u043f\u043e-\u0431\u0430\u0432\u043d\u043e, \u043f\u0440\u0438 \u043a\u043e\u0435\u0442\u043e \u043f\u044a\u0440\u0432\u0430\u0442\u0430 \u043e\u043f\u0430\u043a\u043e\u0432\u043a\u0430 \u043c\u043e\u0436\u0435 \u0434\u0430 \u0432\u0438 \u0441\u0442\u0438\u0433\u043d\u0435 \u0437\u0430 \u0434\u043e 90 \u0434\u043d\u0438.<\/span><\/p><p><span style=\"font-weight: bold; color: #171822; font-family: Roboto, sans-serif; letter-spacing: 0.16px; white-space-collapse: collapse;\">\u0410\u043a\u043e \u0412\u0438 \u0435 \u0445\u0430\u0440\u0435\u0441\u0430\u043b\u0430 \u0441\u0442\u0430\u0442\u0438\u044f\u0442\u0430, \u043c\u043e\u043b\u044f \u043f\u043e\u0441\u043b\u0435\u0434\u0432\u0430\u0439\u0442\u0435 \u043c\u0435 \u0438 \u0432 \u0441\u043e\u0446\u0438\u0430\u043b\u043d\u0438\u0442\u0435 \u043c\u0440\u0435\u0436\u0438:<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-980e591 elementor-shape-rounded elementor-grid-0 e-grid-align-center elementor-widget elementor-widget-social-icons\" data-id=\"980e591\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"social-icons.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-social-icons-wrapper elementor-grid\" role=\"list\">\n\t\t\t\t\t\t\t<span class=\"elementor-grid-item\" role=\"listitem\">\n\t\t\t\t\t<a class=\"elementor-icon elementor-social-icon elementor-social-icon-facebook elementor-repeater-item-7b999bf\" href=\"https:\/\/www.facebook.com\/profile.php?id=100066796167276\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-screen-only\">Facebook<\/span>\n\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"fab fa-facebook\"><\/i>\t\t\t\t\t<\/a>\n\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<span class=\"elementor-grid-item\" role=\"listitem\">\n\t\t\t\t\t<a class=\"elementor-icon elementor-social-icon elementor-social-icon-instagram elementor-repeater-item-d891b47\" href=\"https:\/\/www.instagram.com\/drdimitarmarinov\/\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-screen-only\">Instagram<\/span>\n\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"fab fa-instagram\"><\/i>\t\t\t\t\t<\/a>\n\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<span class=\"elementor-grid-item\" role=\"listitem\">\n\t\t\t\t\t<a class=\"elementor-icon elementor-social-icon elementor-social-icon-linkedin elementor-repeater-item-d66638e\" href=\"https:\/\/www.linkedin.com\/in\/dimitar-marinov-md\/\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-screen-only\">Linkedin<\/span>\n\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"fab fa-linkedin\"><\/i>\t\t\t\t\t<\/a>\n\t\t\t\t<\/span>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1cc85af elementor-widget elementor-widget-text-editor\" data-id=\"1cc85af\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2 dir=\"ltr\" style=\"margin-top: 18pt; margin-bottom: 6pt; font-family: Roboto, sans-serif; line-height: 1.38;\"><span style=\"font-size: 16pt; font-family: Arial, sans-serif; color: #000000; background-color: transparent; font-weight: 400; font-variant-ligatures: normal; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; vertical-align: baseline; white-space-collapse: preserve;\">\u0418\u0437\u0442\u043e\u0447\u043d\u0438\u0446\u0438<\/span><\/h2><ol style=\"line-height: 1.85714em; list-style: upper-decimal; letter-spacing: 0.16px;\"><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6474072\/\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/www.ncbi.nlm.nih.gov<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21517658\/\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/pubmed.ncbi.nlm.nih.gov<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7088919\/\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/www.ncbi.nlm.nih.gov<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7878668\/\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/www.ncbi.nlm.nih.gov<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/www.ema.europa.eu\/en\/medicines\/human\/EPAR\/victoza\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/www.ema.europa.eu<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26074046\/\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/pubmed.ncbi.nlm.nih.gov<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/www.ema.europa.eu\/en\/medicines\/human\/EPAR\/saxenda\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/www.ema.europa.eu<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29225111\/\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/pubmed.ncbi.nlm.nih.gov<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4052428\/\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/www.ncbi.nlm.nih.gov<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6472499\/\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/www.ncbi.nlm.nih.gov<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3594872\/\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/www.ncbi.nlm.nih.gov<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3280675\/\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/www.ncbi.nlm.nih.gov<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6429395\/\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/www.ncbi.nlm.nih.gov<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5424770\/\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/www.ncbi.nlm.nih.gov<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33309563\/\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/pubmed.ncbi.nlm.nih.gov<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26132939\/\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/pubmed.ncbi.nlm.nih.gov<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26284720\/\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/pubmed.ncbi.nlm.nih.gov<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23812094\/\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/pubmed.ncbi.nlm.nih.gov<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa1916038\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/www.nejm.org<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1464-5491.2009.02666.x\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/onlinelibrary.wiley.com<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/diabetesjournals.org\/care\/article\/32\/1\/84\/28994\/Efficacy-and-Safety-Comparison-of-Liraglutide\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/diabetesjournals.org<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(08)61246-5\/fulltext\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/www.thelancet.com<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/diabetesjournals.org\/care\/article\/32\/7\/1224\/26658\/Efficacy-and-Safety-of-the-Human-Glucagon-Like\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/diabetesjournals.org<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/link.springer.com\/article\/10.1007\/s00125-009-1472-y\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/link.springer.com<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(09)60659-0\/fulltext\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/www.thelancet.com<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27350545\/\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/pubmed.ncbi.nlm.nih.gov<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27295427\/\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/pubmed.ncbi.nlm.nih.gov<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5118235\/\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/www.ncbi.nlm.nih.gov<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/alz-journals.onlinelibrary.wiley.com\/doi\/abs\/10.1002\/alz.057848\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: 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href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8881610\/\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/www.ncbi.nlm.nih.gov<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9268041\/\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/www.ncbi.nlm.nih.gov<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2107519\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/www.nejm.org<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8017323\/\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/www.ncbi.nlm.nih.gov<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/www.drugs.com\/sfx\/liraglutide-side-effects.html\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/www.drugs.com<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25504028\/\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/pubmed.ncbi.nlm.nih.gov<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32127832\/\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/pubmed.ncbi.nlm.nih.gov<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8203194\/\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/www.ncbi.nlm.nih.gov<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8307742\/\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/www.ncbi.nlm.nih.gov<\/span><\/a><\/li><li dir=\"ltr\" style=\"line-height: 1.38;\" role=\"presentation\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5358074\/\"><span style=\"font-size: 12pt; font-family: Arial, sans-serif; color: #1155cc; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; text-decoration-line: underline; text-decoration-skip-ink: none; vertical-align: baseline; white-space-collapse: preserve;\">https:\/\/www.ncbi.nlm.nih.gov<\/span><\/a><\/li><\/ol>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Evidence-based 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